Phase 3 Uveitis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are a man or a woman who is not pregnant, are at least 18 years old, are in good general health, and are able to read and understand the consent forms.
• You are willing and able to attend all scheduled appointments and follow the study plan.
• You have been diagnosed with long-term (chronic) inflammation in the back of one or both eyes (not caused by infection), with or without inflammation in the front of the eye.
• Your eye inflammation previously responded to steroid treatment (such as eye drops, injections, or tablets) but came back after treatment, showing it is a long-term condition.
• Your eye inflammation is currently active, as confirmed by your doctor.
• The level of cloudiness in the jelly-like fluid inside your eye (called vitreous haze) is rated at 2 or higher on a standard medical scale.
• There is relatively low cell activity in the front part of your eye, as measured during a specialist eye examination.
• You are not planning to have any optional eye surgery during the study period.

Who may not be able to join:

• You have a known allergy or sensitivity to any ingredient in the study treatment (called YUTIQ).
• You are pregnant or breastfeeding.
• You have a serious ongoing physical or mental health condition that your doctor believes could make participation risky or unsuitable.
• Your eye inflammation has only ever affected the front of the eye, never the back.
• You have bleeding inside the eye (vitreous hemorrhage).
• Your eye inflammation is caused by an infection.
• Your eye inflammation is caused by something other than non-infectious uveitis, such as eye lymphoma.
• You currently have an active infection of the cornea, conjunctiva, or other eye structures, including certain bacterial or fungal eye infections.
• You have a certain type of artificial lens implanted at the front of your eye, or the back part of your natural lens capsule is damaged (confirm with trial site).
• You have been diagnosed with glaucoma or high eye pressure, unless it is well-controlled with two or fewer eye pressure-lowering medications or has been treated with surgery resulting in stable, normal eye pressure.
• Your eye pressure is above 21 mmHg or you are currently using more than two eye pressure-lowering medications.
• You have had any eye surgery within the 12 weeks before the study starts.
• You are unable to attend all follow-up visits over the 12-month study period.
• There is significant cloudiness or opacity in your eye that prevents proper examination of the back of the eye.

Important: Always verify eligibility with the trial site directly before applying.