Long COVID Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are 18 years old or older
- You have had a confirmed COVID-19 infection, proven by a positive PCR test, antigen test, or antibody test, and you have documentation of that positive result
- You have had at least one symptom that started during your COVID-19 illness (or got worse during it) and that symptom has continued for at least 90 days since you first got sick
- You have reduced exercise capacity compared to before COVID, either shown by a formal test or based on what you report yourself
- You are willing and able to attend at least 12 in-person cardiac rehabilitation sessions at UCSF Parnassus (this applies to the active treatment group only)
- You agree to take part in a related study called the LIINC Study, including its heart health sub-study, if you are not already enrolled in it
Who may not be able to join:
- You are pregnant or plan to become pregnant during the study
- You have a pre-existing heart condition such as a heart defect present from birth, heart failure, high blood pressure in the lungs, or you have had a heart or lung transplant, or heart valve surgery
- You have had a heart attack, coronary bypass surgery, or a new diagnosis of significantly reduced heart pumping function within the last 90 days
- You have been diagnosed with heart muscle inflammation (myocarditis) within the last 90 days
- You have an irregular heart rhythm condition such as atrial fibrillation, atrial flutter, or another rhythm problem that requires medication to control it
- You currently take certain heart or blood pressure medications, including beta-blockers, a specific type of calcium channel blocker, or ivabradine (confirm with trial site if unsure about your medications)
- You have an implanted pacemaker or defibrillator
- You have a long-term lung condition that requires you to use oxygen at home
- You are unable to ride a stationary (sitting) bicycle for an exercise test
- You experience severe worsening of symptoms after physical activity that would make it unsafe or impossible to take part in cardiac rehabilitation
- You have other medical or mental health conditions that the lead doctor believes would make it unsafe for you to take part in the trial
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Matthew S Durstenfeld, MD MAS, University of California, San Francisco
Phone: 628-206-5562
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change in adjusted heart rate reserve; Change in Peak VO2 (ml/kg/min)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.