Rare Disease Trial, Recruiting NCT05544266 Sponsor: University of South Florida Condition: Rare Disease
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Rare Disease Trial, Recruiting

NCT05544266
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You were diagnosed with type 2 diabetes before puberty or when you were not overweight
  • Multiple family members across generations have diabetes, especially if it started before age 18
  • Your diabetes affects multiple parts of your body or body systems at the same time
  • You have very little body fat in unusual places (a condition called lipodystrophy)
  • Your body weight (BMI) is at a very high or very low extreme
  • You have muscle weakness or hearing problems alongside your diabetes (confirm with trial site)
  • Your diabetes has stayed stable and has not gotten worse over time
  • Your diabetes progressed very rapidly after diagnosis
  • You need very low doses of insulin (less than 0.5 units per kilogram of body weight per day)
  • Your blood sugar levels go up and down in cycles, with periods where they return to normal
  • You are a lean person with polycystic ovarian syndrome (PCOS)
  • You had diabetes during pregnancy (gestational diabetes) when you were not overweight
  • You are lean but your body does not respond well to insulin
  • Your diabetes does not fit the typical pattern based on specific blood test results related to insulin-producing cells (confirm with trial site)

Who may not be able to join:

  • People who clearly have typical type 1 diabetes, typical type 2 diabetes, a known inherited single-gene form of diabetes, or another already-identified cause of diabetes
  • People who do not agree to genetic testing
  • People who test positive for certain immune markers related to diabetes (though exceptions may be made if other unusual features are present — confirm with trial site)
  • Women who are currently pregnant

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Jeffrey Krischer, PhD, University of South Florida

Phone: 813-396-9501

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
University of South Florida
Registry
ClinicalTrials.gov
Start date
30 September 2020
Est. completion
1 September 2030

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Phenotypic and genotypic characterization of previously unknown forms of diabetes using Whole Genome Sequencing (WGS), and deeper phenotyping methods

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov