OCD Trial, Recruiting NCT05577598 Sponsor: Medical University of Vienna Condition: OCD
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OCD Trial, Recruiting

NCT05577598
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You score 25 or higher on a standard OCD severity scale called the Yale-Brown Obsessive Compulsive Scale.
  • You have tried at least two different medications from the SSRI (serotonin reuptake inhibitor) family, each at the highest recommended dose (if you could tolerate it), for at least 10 weeks each, and they did not help enough.
  • You have also tried at least one older type of antidepressant called a tricyclic medication, at the highest recommended dose (if tolerated), for at least 10 weeks, without enough improvement.
  • You have tried at least one additional medication added on top of another treatment, such as an antipsychotic, lithium, a calming medication (benzodiazepine), or buspirone.
  • You have completed at least 20 sessions of talking therapy, such as Cognitive Behavioral Therapy (CBT) or a similar approach.
  • You are able to read, understand, and sign a consent form agreeing to take part in the study.

Who may not be able to join:

  • You have ever had, or currently have, a condition involving psychosis (losing touch with reality).
  • You have had a manic episode (an extreme high mood episode) within the past three years.
  • You have a significant medical or neurological condition that would make brain stimulation surgery (DBS) unsafe for you.
  • You have a condition that affects how your body processes sugar, such as diabetes.
  • Your pre-surgery brain scan (MRI) shows a significant abnormality, or you are unable to have an MRI scan.
  • You currently have, or have recently had, problems with substance misuse or dependence (not including nicotine/smoking).
  • You are pregnant, planning to become pregnant during the study, or unwilling to use a reliable method of contraception.
  • You currently have a severe personality disorder (except for a specific type called anankastic personality disorder, which may still be allowed).
  • You are unable or unwilling to follow the study's procedures and requirements.
  • You are currently experiencing serious, unstable thoughts of suicide.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Christoph Kraus, MD PhD, Medical University of Vienna, Department of Psychiatry and Psychotherapy

Phone: +43 1 40400 73882

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 April 2022
Est. completion
1 May 2026

Where this trial is recruiting

🇦🇹 Austria

Primary endpoints

Change of metabolic rates of glucose response pattern

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov