Phase 3 Leukaemia Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are 18 years of age or older at the time of joining the trial
• People who have been diagnosed with a specific type of blood cancer called acute myeloid leukemia (AML), either as a primary condition or developed from a prior blood disorder called myelodysplastic syndrome (MDS), as classified by World Health Organization (WHO) standards
• People whose AML either did not respond to their first round of treatment, or came back after their first round of treatment (with or without a stem cell transplant)
• People who test positive for a specific gene change called a FLT3 mutation, confirmed by a central laboratory using a bone marrow or blood sample
• People who have a general health and activity level rated at 0, 1, or 2 on a standard medical scale (meaning able to carry out daily activities with little to no limitation)
• People for whom the treating doctor considers a specific type of follow-up chemotherapy (called salvage chemotherapy) to be appropriate

Who may not be able to join:

• People who have previously been treated with any medication that targets the FLT3 mutation (known as FLT3 inhibitors)
• People whose AML has returned or stopped responding after more than one round of treatment
• People who currently have an active infection that is not under control
• People who are known to have HIV (human immunodeficiency virus)
• People who have any other health condition that, in the treating doctor's judgement, would make participation in the trial unsuitable

Important: Always verify eligibility with the trial site directly before applying.