Phase 1 Obesity Trial, Recruiting NCT05589688 Sponsor: University Hospital, Toulouse Condition: Obesity
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Phase 1 Obesity Trial, Recruiting

NCT05589688
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Healthy volunteers with a BMI between 18 and 39.9 (the trial is looking for people across four weight ranges: normal weight, overweight, grade 1 obesity, and grade 2 obesity)
  • People whose kidneys are working at a sufficient level (a kidney function score above 50 ml/min, as measured by a specific test — confirm with trial site)
  • People with good, accessible veins suitable for blood sample collection
  • Women who are either using contraception or who have gone through menopause
  • People who are able to give written consent and are enrolled in the public health insurance system

Who may not be able to join:

  • People taking certain medications that could affect the kidneys or interact with the study drug, including diuretics (water pills), anti-inflammatory painkillers (such as ibuprofen), or statins (cholesterol-lowering drugs)
  • People who have had a serious allergic reaction to any medication (such as severe swelling) or who have significant organ problems such as liver failure or heart failure
  • People who have diabetes or who take diabetes medications
  • People who have high blood pressure or who take blood pressure medications
  • People taking medications that are known to interact with the study drug acyclovir, including certain stomach acid medications, Probenecid, Mycophenolate Mofetil, Lithium, or immune-suppressing drugs such as Ciclosporin or Tacrolimus
  • People currently taking blood-thinning medications (anticoagulants)
  • People who have a known allergy or sensitivity to acyclovir
  • People who are pregnant
  • People who have taken part in another clinical study within the last two months
  • People who currently have an active HSV or VZV viral infection (such as cold sores, genital herpes, or shingles) being treated with acyclovir
  • Adults who are under legal guardianship, any other form of legal protection, or who are restricted in their freedom by a court or government decision

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 13 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Sarah Baklouti, PharmD, University Hospital, Toulouse

Phone: 05 67 69 03 83

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Registry
ClinicalTrials.gov
Start date
9 April 2024
Est. completion
1 December 2026

Where this trial is recruiting

🇫🇷 France

Primary endpoints

Renal elimination clearance

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov