Brain Cancer Trial, Recruiting NCT05595577 Sponsor: Wake Forest University Health Sciences Condition: Brain Cancer
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Brain Cancer Trial, Recruiting

NCT05595577
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults between 18 and 85 years old
  • People who have been diagnosed with stage I–IV Hodgkin's or non-Hodgkin's lymphoma, or stage I–III breast cancer
  • People who are expected to receive certain cancer treatments, including specific types of chemotherapy (such as anthracyclines, trastuzumab, or rituximab), immunotherapy (immune checkpoint inhibitors), or radiation therapy (within 8 weeks of finishing radiation)
  • People who are able to speak and understand English
  • People who are able to walk at least 2 city blocks (roughly 0.2 miles) on a flat surface without difficulty
  • People whose doctors expect them to survive beyond 6 months
  • People who have a helper available to assist with at-home testing activities

Who may not be able to join:

  • People with very high blood pressure that is not under control (top number above 190 or bottom number above 100)
  • People with a recent history of alcohol or drug misuse, active inflammatory conditions such as lupus or inflammatory bowel disease, or other serious health conditions that could affect safety — though stable chronic conditions may be considered with approval from the person's doctor and the trial's lead researcher
  • People with certain metal implants or electronic devices in their body that are not compatible with MRI scans, such as some types of brain surgery clips, pacemakers, defibrillators, or nerve stimulators — unless approved by the person's doctor and the trial's lead researcher
  • People who are pregnant
  • People with unstable angina (a serious, unpredictable type of chest pain)
  • People for whom exercise testing or training is medically unsuitable
  • People who are unable to exercise on a treadmill or stationary bike
  • People with significant irregular heartbeats of a specific type (more than 20 extra ventricular beats per minute)
  • People with a type of irregular heart rhythm called atrial fibrillation where the heart rate is not well controlled
  • People who have had a heart attack within the past 28 days
  • People who are not able to give informed consent to participate

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: William Hundley, MD, Wake Forest Baptist Comprehensive Cancer Center

Phone: 336-758-3027

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 March 2023
Est. completion
31 August 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in Peak VO2

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov