Tuberculosis Trial, Recruiting NCT05610098 Sponsor: University of Cape Town Condition: Tuberculosis
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Tuberculosis Trial, Recruiting

NCT05610098
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have signed a consent form before any assessments begin and are willing to have an HIV test
  • You have been diagnosed with tuberculosis (TB) of the spine, based on your symptoms and imaging scans (such as an X-ray or MRI)
  • You are 18 years of age or older and weigh at least 40 kg (about 88 lbs)
  • You are able and willing to attend follow-up appointments during the trial
  • You are willing to have biological samples (including genetic material) collected and stored for research
  • You are willing to use a reliable method of contraception (pregnancy prevention) throughout the trial

Who may not be able to join:

  • You are currently pregnant or are planning to become pregnant within the next 6 months
  • You have diabetes that is not well controlled, based on certain blood sugar test results (confirm with trial site)
  • You have issues with alcohol or substance use that could make it difficult to take medications as required during the trial
  • You have tested positive for COVID-19 (via PCR test) within the past 4 weeks
  • There is a suspicion of cancer based on your MRI scan, or you have a known cancer diagnosis
  • There is a suspicion that your symptoms may be caused by an inflammatory condition or a rheumatological (joint or immune-related) disease rather than TB
  • Your doctor feels, for any reason, that this trial is not right for you (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: friedrich Thienemann, MD, University of Cape Town

Phone: +27 (0)21 406 6358

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
University of Cape Town
Registry
ClinicalTrials.gov
Start date
25 October 2022
Est. completion
31 December 2025

Where this trial is recruiting

🇿🇦 South Africa

Primary endpoints

Clinical phenotype of spinal TB; mRNA gene expression profiles of spinal TB

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov