Phase 3 PTSD Trial, Recruiting NCT05637879 Sponsor: White River Junction Veterans Affairs Medical Center Condition: PTSD
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Phase 3 PTSD Trial, Recruiting

NCT05637879
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People between 19 and 70 years of age
  • People who weigh at least 45 kg (approximately 99 lbs)
  • People who have been diagnosed with PTSD using a specific clinical assessment (called the CAPS-5), completed within seven days of enrolling in the trial
  • People who are eligible to receive healthcare through the Veterans Affairs (VA) system
  • People who are capable of becoming pregnant must be using an accepted form of birth control, such as effective contraceptives, or practicing abstinence
  • People who are able to read, understand, and sign the consent form for the trial

Who may not be able to join:

  • People who are currently pregnant or breastfeeding
  • People with moderate or severe liver problems (known as Child-Pugh B or C)
  • People who have previously experienced serious liver failure
  • People currently taking certain medications that are known to interact significantly with the trial drug (confirm with trial site for the specific list)
  • People with advanced liver disease
  • People with a current or past hepatitis B infection
  • People who have previously been treated with the specific drug combination used in this trial, or certain related liver medications (confirm with trial site)
  • People who currently have a hepatitis C infection
  • People who are currently experiencing psychosis or mania
  • People with significant thoughts of suicide
  • People with unstable medical conditions
  • People with a current severe alcohol or drug use disorder (not including nicotine)
  • People who have changed or started a recognised PTSD-focused therapy program within the past two months
  • People who have changed or started a recognised PTSD medication within the past two months

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 20 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Bradley V Watts, MD, MPH, US Department of Veterans Affairs

Phone: 802-295-9363

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
White River Junction Veterans Affairs Medical Center
Registry
ClinicalTrials.gov
Start date
18 December 2023
Est. completion
31 December 2025

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Clinical Administered Post-Traumatic Stress Disorder Scale version 5 (CAPS-5)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov