PTSD Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged between 18 and 55 years old
• People who are able to have a specific type of brain stimulation test called single pulse TMS performed safely and with a measurable response
• People who are able to safely and comfortably undergo both an MRI scan and TMS (a type of non-invasive brain stimulation)
• People who are able to read, understand, and willingly sign a consent form before any study procedures begin
• People who have been diagnosed with PTSD according to standard diagnostic guidelines (DSM-5), confirmed through a structured clinical interview called the CAPS-5
• People who are able to keep their medication routine stable between two brain scanning sessions

Who may not be able to join:

• People for whom an MRI scan would not be safe or comfortable, as determined by the centre conducting the scans
• People for whom TMS would not be safe or comfortable, including anyone with a history or condition that increases risk from this procedure
• People with significant memory or thinking difficulties, as measured by a standard cognitive assessment called the MoCA
• People whose primary condition causing significant daily difficulty is something other than PTSD, or whose other medical or mental health conditions would make it unclear whether symptoms are due to PTSD (confirm with trial site)
• People who urgently need a level of care that would make participating in the study impossible
• People currently taking medications that raise the risk of seizures or that affect blood flow responses in the brain
• People with any other condition that could prevent them from completing the study or make the results difficult to interpret

Important: Always verify eligibility with the trial site directly before applying.