Phase 2 Brain Cancer Trial, Recruiting NCT05653635 Sponsor: Centre Paul Strauss Condition: Brain Cancer
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Phase 2 Brain Cancer Trial, Recruiting

NCT05653635
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are over 18 years old
  • You have been diagnosed with glioblastoma (a type of brain tumour), Grade IV, confirmed by a tissue sample (biopsy or surgery)
  • You are reasonably active and able to care for yourself, with a performance level rated 0, 1, or 2 (a standard scale doctors use to measure how well you function day-to-day)
  • Your neurological (brain and nerve) function meets a minimum level of at least 2 on the scale used in this trial (confirm with trial site)
  • You have previously received radiation treatment in or near the area of the brain being considered for re-treatment (within about 5–7 cm)
  • Scans have confirmed that your tumour has come back, based on specific medical guidelines (confirm with trial site)
  • There is still some tumour remaining after you had partial surgery following the recurrence
  • You have between 1 and 3 areas where the tumour has returned, each smaller than 35 mm across, and at least 5 mm apart from each other
  • Each returning tumour area is smaller than 35 mL in volume
  • The returning tumour(s) are more than 10 mm away from your optic nerves, the point where the optic nerves cross (chiasma), and the brain stem

Who may not be able to join:

  • You are unable to have an MRI scan or a PET scan for any medical reason
  • You have a widespread form of glioblastoma affecting a large area of the brain (glioblastomatose)
  • You are pregnant or currently breastfeeding
  • You do not understand French
  • You are not enrolled in the French national or local social security system
  • You are unable to attend and follow the trial's required appointments and assessments due to where you live, your social situation, or psychological reasons
  • You are under 18 years old, or are under legal guardianship or supervision
  • You are currently deprived of your liberty (for example, in custody)
  • You are under judicial protection (a legal status in France) (confirm with trial site)
  • You are not able to give your own informed consent to take part

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 5 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: (0)388252413

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Centre Paul Strauss
Registry
ClinicalTrials.gov
Start date
1 March 2026
Est. completion
1 September 2028

Where this trial is recruiting

🇫🇷 France

Primary endpoints

Efficacy of simultaneous-integrated boost with IMRT guided by FDOPA PET on Recurrence free survival in patient with recurrent glioblastoma

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 5 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov