PTSD Trial, Recruiting NCT05662423 Sponsor: Massachusetts General Hospital Condition: PTSD
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PTSD Trial, Recruiting

NCT05662423
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Women who have recently given birth at Massachusetts General Hospital (MGH).
  • Women who score higher than 16 on a screening tool called the Peritraumatic Distress Inventory (PDI), which suggests they may be at risk of developing trauma-related stress connected to childbirth.

Who may not be able to join:

  • Women younger than 18 or older than 50 years of age.
  • Women whose baby was stillborn.
  • Women whose baby was born with Down's Syndrome, another serious genetic condition, or a serious birth defect such as microcephaly or spina bifida.
  • Women whose baby was admitted to the newborn intensive care unit (NICU) for more than one week, or whose baby is not in good medical health.
  • People currently diagnosed with a psychotic disorder, bipolar disorder, or a substance use disorder as defined by DSM-5 criteria (confirm with trial site).
  • People assessed as being actively at risk of suicide (assessed on a case-by-case basis by the trial site).
  • People whose medical records indicate current substance misuse.
  • Women experiencing serious health complications related to childbirth (assessed on a case-by-case basis by the trial site).
  • Women who received general anaesthesia during their birth.
  • People who are unable to fully understand the study procedures, risks, and side effects, or who are unable to give informed consent for any neurological or other reason.
  • People who are unable to understand English.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 617-726-1352

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
8 November 2023
Est. completion
20 July 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change from baseline in the PTSD Checklist for DSM-5 (PCL-5) total score; Change from baseline in the PTSD Checklist for DSM-5 (PCL-5) total score; Physiological reactivity as determined from psychophysiologic responses during script-driven traumatic memory recollection of recent childbirth; Clinician-Administered PTSD-5 Scale for DSM 5 (CAPS-5)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov