Phase 3 Head and Neck Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been newly diagnosed with a specific type of nasopharyngeal cancer (a cancer at the back of the nose/throat), confirmed by tissue biopsy, classified as WHO type II or III (non-keratinizing type).
• People aged between 18 and 70 years old.
• People whose cancer is at stage III or IVa, based on a standard cancer staging system (the 8th edition AJCC staging system).
• People who had a detectable level of a virus marker (EBV DNA) in their blood before treatment, which then became undetectable after one round of pre-treatment chemotherapy, and stayed undetectable during the second and third rounds.
• People who have a good general health and activity level, rated 0 or 1 on a standard medical scale (meaning largely active and able to carry out daily activities with little or no restriction).
• People whose blood test results meet specific minimum levels for red blood cells, white blood cells, and platelets (confirm with trial site for exact values).
• People whose liver function blood tests fall within an acceptable range, specifically certain liver enzymes and bilirubin levels (confirm with trial site for exact values).
• People whose kidney function blood tests fall within an acceptable range, based on a measure called serum creatinine (confirm with trial site for exact values).
• People who are willing and able to follow all trial requirements, including visits, treatments, and tests, and who are able to provide signed consent to participate.

Who may not be able to join:

• People whose biopsy confirms a different type of nasopharyngeal cancer, specifically keratinizing squamous cell carcinoma (WHO type I).
• People who have previously had another type of cancer, with the exception of certain treated skin cancers (basal cell carcinoma) or early-stage cervical cancer that has been fully treated.
• People who have previously received radiotherapy, chemotherapy, or targeted cancer therapy.
• People who are pregnant or currently breastfeeding.
• People who have significantly reduced function of the heart, liver, lungs, kidneys, or bone marrow.
• People who have serious or poorly controlled medical conditions or active infections.
• People who are currently participating in another clinical trial or taking another experimental drug.
• People who are unwilling or unable to provide signed consent to participate.
• People who have an emotional disturbance or mental illness that affects their legal capacity to make decisions (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.