Phase 2 Brain Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are 18 years of age or older.
• People diagnosed with a specific type of lung cancer (non-squamous) that is locally advanced, classified as stage IIIA, IIIB, or IIIIC according to standard cancer staging guidelines.
• People whose lung cancer tissue analysis shows a mixed cell type (adeno-squamous) or results that are not clearly categorised but lean toward squamous are also considered eligible.
• People who are enrolled and have their first brain MRI scan at around 120 days (plus or minus 10 days) from the start of their radiation therapy for lung cancer — enrolment can happen before or after radiation therapy begins.
• People with a general health and activity level rated between 0 and 3 on a standard medical scale (ranging from fully active to limited self-care; confirm with trial site).
• People whose kidneys are functioning at a sufficient level, as measured by a specific blood test result (confirm with trial site for details).
• People who are safe to undergo a brain MRI scan, as determined by a safety screening checklist completed by relevant medical staff at the trial site.

Who may not be able to join:

• People who already have confirmed cancer that has spread to the brain, as seen on their initial staging MRI scan.
• People who are currently pregnant or breastfeeding.
• People who could potentially become pregnant and do not have a negative pregnancy test taken within 14 days of enrolling in the trial (this requirement does not apply to people who have gone through menopause or have had certain surgeries such as removal of the uterus or ovaries, or have a medically confirmed condition that prevents pregnancy).

Important: Always verify eligibility with the trial site directly before applying.