PTSD Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 18 to 70 years old
- People who can read and write English well enough to complete questionnaires and take part in interviews
- People who have come to the Rush Emergency Department with sudden, acute pain that is not caused by a serious physical injury
- People who have one main area of acute pain
- People who report symptoms that match a diagnosis of PTSD (Post-Traumatic Stress Disorder)
- People with well-controlled diabetes or HIV/AIDS who have long-term nerve pain, as long as the acute pain they came to the Emergency Department with is not related to that nerve pain
- People with a history of psychosis or bipolar disorder that is currently well managed, have been receiving treatment for at least 3 months, can clearly answer interview questions, and are considered by study staff to be able to participate
- People who have an ongoing illness that involves frequent or constant pain, as long as the acute pain they came in with is unrelated to that ongoing illness (considered on a case-by-case basis)
- People who have ongoing chronic pain from various causes, as long as the acute pain they came in with is unrelated to their existing chronic pain (considered on a case-by-case basis)
Who may not be able to join:
- People whose pain is severe enough to affect their concentration or ability to understand instructions, as assessed by a medical staff member
- People whose injury or illness prevents them from understanding or following instructions, as assessed by a medical staff member
- People who report a history of long-term chronic pain when arriving at the Emergency Department, or whose medical records show a history of chronic pain (considered on a case-by-case basis)
- People whose pain is coming from the same traumatic event that is the source of their PTSD
- People who have a neurological disorder (a condition affecting the brain or nervous system)
- People whose blood pressure is higher than 160/100 mmHg at the time of the study
- People who are taking blood-thinning medications or anti-clotting drugs, other than aspirin
- People who are pregnant
- People who are currently dependent on alcohol or other substances
- People whose circumstances would prevent the trial's treatments from working effectively (confirm with trial site)
- People currently being treated for certain significant conditions, such as rheumatoid disease, active influenza that may be causing pain, or heart disease
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: John W Burns, PhD, Rush University Medical Center
Phone: 312-942-0379
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Pain Intensity; Change in PTSD Checklist for Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (PCL-5) Self-Reported PTSD Symptoms
Can't join this trial?
Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.