PTSD Trial, Recruiting NCT05700279 Sponsor: Rush University Medical Center Condition: PTSD
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PTSD Trial, Recruiting

NCT05700279
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 to 70 years old
  • People who can read and write English well enough to complete questionnaires and take part in interviews
  • People who have come to the Rush Emergency Department with sudden, acute pain that is not caused by a serious physical injury
  • People who have one main area of acute pain
  • People who report symptoms that match a diagnosis of PTSD (Post-Traumatic Stress Disorder)
  • People with well-controlled diabetes or HIV/AIDS who have long-term nerve pain, as long as the acute pain they came to the Emergency Department with is not related to that nerve pain
  • People with a history of psychosis or bipolar disorder that is currently well managed, have been receiving treatment for at least 3 months, can clearly answer interview questions, and are considered by study staff to be able to participate
  • People who have an ongoing illness that involves frequent or constant pain, as long as the acute pain they came in with is unrelated to that ongoing illness (considered on a case-by-case basis)
  • People who have ongoing chronic pain from various causes, as long as the acute pain they came in with is unrelated to their existing chronic pain (considered on a case-by-case basis)

Who may not be able to join:

  • People whose pain is severe enough to affect their concentration or ability to understand instructions, as assessed by a medical staff member
  • People whose injury or illness prevents them from understanding or following instructions, as assessed by a medical staff member
  • People who report a history of long-term chronic pain when arriving at the Emergency Department, or whose medical records show a history of chronic pain (considered on a case-by-case basis)
  • People whose pain is coming from the same traumatic event that is the source of their PTSD
  • People who have a neurological disorder (a condition affecting the brain or nervous system)
  • People whose blood pressure is higher than 160/100 mmHg at the time of the study
  • People who are taking blood-thinning medications or anti-clotting drugs, other than aspirin
  • People who are pregnant
  • People who are currently dependent on alcohol or other substances
  • People whose circumstances would prevent the trial's treatments from working effectively (confirm with trial site)
  • People currently being treated for certain significant conditions, such as rheumatoid disease, active influenza that may be causing pain, or heart disease

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 12 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: John W Burns, PhD, Rush University Medical Center

Phone: 312-942-0379

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Rush University Medical Center
Registry
ClinicalTrials.gov
Start date
1 September 2023
Est. completion
1 February 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Pain Intensity; Change in PTSD Checklist for Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (PCL-5) Self-Reported PTSD Symptoms

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov