Phase 1 Kidney Cancer Trial, Recruiting NCT05700461 Sponsor: Oliver Jonas Condition: Kidney Cancer
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Phase 1 Kidney Cancer Trial, Recruiting

NCT05700461
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You must be able to understand the study and be willing to sign a consent form agreeing to take part.
  • You must have confirmed or suspected kidney cancer (either in one location or that has spread), and your doctors must already be planning to remove the tumor or a spread of the cancer through surgery, with the tumor being at least 1cm in size.
  • You must be 18 years of age or older.
  • You must be seen by a cancer specialist (oncologist) who will decide the best treatment plan for you based on your situation.
  • Your doctors must consider you healthy enough to safely have both a needle-based procedure and your planned surgery.
  • You must have blood test results within an acceptable range taken within 30 days before the procedure, showing your immune cells, platelets, and blood clotting levels are at safe levels.
  • You must have already had a CT scan or MRI as part of your normal care that shows the extent of your cancer.
  • Your case must be reviewed by a specialist in image-guided procedures (interventional radiology) and a surgical specialist to confirm the tumor is suitable for a small research device to be placed into it and removed during surgery.
  • You must be willing to have your genetic information studied (from both the tumor and your normal cells) and agree to have your anonymized genetic data stored in a secure government research database.

Who may not be able to join:

  • You may not be able to join if you have an uncontrolled illness, such as an active infection, serious heart problems, or a mental health or personal situation that would make a biopsy or surgery unsafe.
  • You may not be able to join if you have a bleeding or clotting disorder that cannot be treated or corrected and that would increase the risk of a biopsy or surgery.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Wenxin Xu, MD, Dana-Farber Cancer Institute

Phone: 617-632-6534

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Oliver Jonas
Registry
ClinicalTrials.gov
Start date
1 December 2024
Est. completion
31 October 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Safety of microdevice implantation; Number of Patients with Feasible Microdevice Procedure

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov