Obesity Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have signs and symptoms of heart failure
- People whose heart is pumping at a rate greater than 50% of its normal capacity (known as an ejection fraction above 0.50)
- People with measurable evidence that their heart muscle is not relaxing properly between beats (diastolic dysfunction), including those with elevated levels of a specific heart stress marker in their blood (NT-proBNP above 300 ng/dl) or who have previously been hospitalised due to heart failure
- Healthy volunteers with no heart condition
Who may not be able to join:
- People under 55 years of age
- People with a body mass index (a measure of body weight relative to height) above 50
- People who have an irregular heart rhythm called atrial fibrillation where the heart rate is not well controlled
- People who are currently taking a type of medication called PDE5 inhibitors (used for conditions such as erectile dysfunction or pulmonary hypertension)
- People with serious problems affecting the valves in their heart
- People with a severe form of a long-term lung condition called chronic obstructive pulmonary disease (COPD)
- People with significantly reduced kidney function, classified as chronic kidney disease stage 4 or worse
- People who have any condition that limits their ability to walk or move around freely
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Tony G Babb, Ph.D., University of Texas Southwestern Medical Center
Phone: 214-345-6574
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
O2 cost of breathing (Objective 1); Change in DOE during HeO2 breathing (Objective 2); Change in peak exercise capacity during HeO2 breathing (Objective 2)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.