Spinal Muscular Atrophy Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are willing to sign a consent form and agree to follow all study procedures for the full duration of the trial.
- You are between 3 and 17 years old.
- You have a walking difficulty related to the knee joint, caused by cerebral palsy, muscular dystrophy, spina bifida, or an incomplete spinal cord injury.
- Your knee can bend and straighten by at least 25 degrees when lying on your back with your hip flat (confirm with trial site).
- Your ankle can move up and down by at least 15 degrees when the foot is in a neutral position (confirm with trial site).
- The angle of your foot relative to your thigh, when lying face down, falls within a specific range (confirm with trial site).
- You are able to walk at least 10 feet without stopping, with or without a walking aid.
Who may not be able to join:
- You have any other nerve, muscle, bone, heart, or breathing condition — beyond the four listed diagnoses — that would affect your ability to walk while wearing a robotic leg brace.
- You have had uncontrolled seizures at any point in the past year.
- You are pregnant (a urine test will be done at the first visit for anyone who could become pregnant, and self-reporting will be used throughout the study).
- You have a heart or lung condition that means you cannot exercise for at least 60 minutes per session or at least 5 days per week.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Thomas C Bulea, Ph.D., National Institutes of Health Clinical Center (CC)
Phone: (301) 451-7533
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
To evaluate the effectiveness of a longitudinal exoskeleton training program in the community, as opposed to a standard regimen of therapy of the same magnitude, at improving knee extension deficiency in children with CP, SB, iSCI or MD.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.