Phase 2 Leukaemia Trial, Recruiting NCT05736965 Sponsor: Shanghai Tong Ren Hospital Condition: Leukaemia
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Phase 2 Leukaemia Trial, Recruiting

NCT05736965
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have given written consent to participate voluntarily
  • People aged 18 years or older
  • People who have been newly diagnosed with acute myeloid leukaemia (AML) and have been assessed as not suitable for intensive chemotherapy, either because they are 75 or older, or because they are aged 18 to 74 and have at least one of the following health conditions: a low activity or functioning level (as rated by their doctor), heart failure requiring treatment or reduced heart pumping function or stable chest pain (angina), reduced lung function based on breathing tests, reduced kidney function within a certain range, moderate liver impairment, or another condition their doctor considers incompatible with intensive chemotherapy
  • People who are medically suitable for intensive chemotherapy but have chosen not to receive it
  • People whose liver function test results fall within the levels specified by the trial (confirm with trial site)
  • People whose kidney function shows a creatinine clearance of at least 30 mL/min, measured using a standard formula
  • People with a life expectancy of at least 4 weeks

Who may not be able to join:

  • People who have a history of other cancers before entering the study (some exceptions may apply — confirm with trial site)
  • People with a known HIV infection, or active hepatitis B or hepatitis C infection
  • People whose AML has spread to the central nervous system (the brain and spinal cord)
  • People who have already received treatment for AML, except for a medication called hydroxyurea

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 18017337037

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Shanghai Tong Ren Hospital
Registry
ClinicalTrials.gov
Start date
20 February 2023
Est. completion
30 March 2025

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Percentage of Participants With Composite Complete Remission

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov