Lung Cancer Trial, Recruiting NCT05746325 Sponsor: Mayo Clinic Condition: Lung Cancer
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Lung Cancer Trial, Recruiting

NCT05746325
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 or older
  • People who have previously been diagnosed with breast cancer or lung cancer through a tissue sample
  • People who have a confirmed diagnosis of cancer that has spread to the membranes surrounding the brain and spinal cord (called leptomeningeal metastases), shown by both a positive spinal fluid test and specific scan findings
  • People who have MRI scan results showing cancer involvement along the cervical, thoracic, or lumbar spine
  • People with a life expectancy of at least 6 weeks
  • People whose general physical functioning falls within a certain range on a standard medical scale (ECOG score of 0–3, where 0 means fully active and 3 means limited self-care) (confirm with trial site)
  • People who have recovered from any nerve-related side effects of previous treatments
  • People whose blood platelet count and white blood cell levels meet minimum thresholds set by the trial (confirm with trial site for exact values)
  • People whose liver and kidney function meet the levels required by the trial (confirm with trial site for exact values)
  • People who are able to give written consent, either personally or through a legal representative
  • People whose body shape and size are suitable for wearing the treatment device
  • People who are willing to wear the device for an average of at least 18 hours per day
  • People who are willing to attend scheduled check-up visits and complete required assessments
  • People who do not have another illness or situation that would make it hard to fairly assess the safety of the treatment
  • People who are able to start the study treatment within 14 days of registering for the trial

Who may not be able to join:

  • People currently receiving certain high-dose chemotherapy drugs, specifically high-dose methotrexate, high-dose thiotepa, or high-dose cytarabine (other systemic cancer treatments are generally permitted)
  • People who have had radiation therapy to the brain or spinal cord within the past 2 weeks
  • People who have had chemotherapy delivered directly into the spinal fluid within the past week
  • People who are pregnant or breastfeeding, or people of childbearing potential who are not willing to use effective contraception
  • People with an uncontrolled or untreated infection, including active hepatitis or HIV
  • People currently taking part in another clinical trial, or who have received an investigational treatment within the past 14 days (or longer, if that treatment is known to have delayed side effects)
  • People with a known allergy to the hydrophilic gel used to attach the treatment device to the skin
  • People who have surgical hardware (such as titanium rods, screws, or fixation devices) in the area of the spine where treatment would be applied

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Wendy J. Sherman, MD, Mayo Clinic

Phone: 855-776-0015

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Registry
ClinicalTrials.gov
Start date
7 April 2023
Est. completion
1 March 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Incidence of significant toxicity of tumor treating fields (TTFs); Feasibility of TTFs - completion of at least 28 days of TTF therapy

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov