Phase 1 Head and Neck Cancer Trial, Recruiting NCT05747625 Sponsor: Eben Rosenthal Condition: Head and Neck Cancer
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Phase 1 Head and Neck Cancer Trial, Recruiting

NCT05747625
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 19 years or older
  • People who have been diagnosed with squamous cell carcinoma (a type of cancer) of the head and neck, confirmed by a biopsy
  • People with head and neck cancer at any stage and in any location within the head and neck area, including those whose cancer has come back or who have developed a new cancer in that area
  • People whose scans (a type of nuclear imaging scan called FDG-PET/CT, or a CT scan) show signs of cancer spread that need further investigation, or a main tumour with suspicious lymph nodes, before surgery
  • People whose blood test results meet certain minimums for haemoglobin (a measure of red blood cells), white blood cells, and platelets (cells that help blood clot)
  • People whose kidney function blood test result falls within an acceptable range

Who may not be able to join:

  • People who have had a heart attack, stroke, uncontrolled heart failure, significant liver disease, or unstable chest pain within the 6 months before enrolling
  • People who have previously had a serious reaction during an infusion of a monoclonal antibody (a type of targeted therapy given through a drip)
  • People who are pregnant or breastfeeding
  • People whose magnesium or potassium blood levels are below the normal range used by the treating institution
  • People who are currently taking certain heart rhythm medications, specifically those in the class IA group (such as quinidine or procainamide) or class III group (such as dofetilide, amiodarone, or sotalol) (confirm with trial site if unsure which category applies)
  • People who have a history of, or signs of, scarring or inflammation in the lungs (conditions known as interstitial pneumonitis or pulmonary fibrosis)
  • People with severe kidney disease or a complete absence of urine production
  • People who are known to have an allergy or sensitivity to a medication called deferoxamine or any of its ingredients

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Michael Topf, MD, Vanderbilt University/Ingram Cancer Center

Phone: 615-936-2807

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Eben Rosenthal
Registry
ClinicalTrials.gov
Start date
9 May 2023
Est. completion
28 February 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Sensitivity of zirconium Zr 89 panitumumab (89Zr-panitumumab; Specificity of 89Zr-panitumumab

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov