Cystic Fibrosis Trial, Recruiting NCT05766774 Sponsor: Emory University Condition: Cystic Fibrosis
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Cystic Fibrosis Trial, Recruiting

NCT05766774
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have a confirmed diagnosis of cystic fibrosis (CF)
  • People who are 18 years of age or older
  • People whose estimated daily added sugar intake is more than 16 teaspoons, based on a dietary questionnaire completed during screening

Who may not be able to join:

  • People who receive nutrition through a feeding tube at night
  • People with a body mass index (BMI) below 18.5, which generally indicates being underweight
  • People whose life expectancy is estimated to be less than 12 months
  • People who have been diagnosed with cystic fibrosis-related diabetes (CFRD)
  • People whose blood sugar level while fasting is found to be 126 mg/dL or higher during a screening glucose test
  • People who use steroid medications on an ongoing, long-term basis
  • People who are currently pregnant or breastfeeding
  • People who are unwilling or unable to eat most of the foods provided as part of the study's meal plan
  • People who have metal implants in their body that cannot be removed and are not compatible with MRI scanning
  • People whose pancreatic digestive problems are not well managed and are causing significant malabsorption of nutrients
  • People who have had recent changes to their medical treatment — including medications or a lung flare-up — within the 21 days before their study visit (confirm with trial site)
  • People who started a CFTR modulator medication within the past 8 weeks, or whose weight or lung function has been unstable due to CFTR modulator use
  • People who are actively working to gain or lose weight at the time of the study
  • People who have food allergies or intolerances that the study team cannot accommodate within the meal plan
  • People who have any other medical condition that a study doctor determines could prevent them from completing the study or could affect the study's results

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Jessica A Alvarez, PhD, RD, Emory University

Phone: 404-727-1390

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
28 June 2023
Est. completion
30 June 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in acute insulin response to arginine (AIRarg) from baseline; Change in acute C-peptide (ACRarg) from baseline; Change in visceral adipose tissue from baseline; Change in fasted plasma Eh[CySS] from baseline

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov