PTSD Trial, Recruiting NCT05780177 Sponsor: VA Office of Research and Development Condition: PTSD
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PTSD Trial, Recruiting

NCT05780177
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are a veteran between the ages of 18 and 75
  • You have been diagnosed with Insomnia Disorder based on standard medical guidelines (DSM-5)
  • You have been diagnosed with PTSD based on standard medical guidelines (DSM-5)
  • If you are taking any medications for sleep, PTSD, or mental health, you have been on a stable dose for at least one month and are willing to keep them unchanged during the active part of the study
  • If you are currently in any type of talk therapy, you have been attending for at least one month and do not plan to stop during the trial; if you plan to start a new therapy, you would need to wait one month before joining
  • If you are currently in — or planning to start — a specific therapy that directly targets insomnia or PTSD (such as CBT for Insomnia, Cognitive Processing Therapy, or Prolonged Exposure Therapy), you would need to finish that treatment and wait one month before being screened for this trial
  • Veterans with a traumatic brain injury (TBI) are not automatically excluded
  • Veterans with chronic pain are not automatically excluded
  • Veterans with treated or untreated sleep apnea, or those considered high-risk for sleep apnea, are not automatically excluded

Who may not be able to join:

  • You have a history of psychotic disorder or manic episodes at any point in your life
  • You have a moderate to severe alcohol or drug use disorder
  • You have shown recent harmful behavior toward others, or you have recent suicidal behavior, a recent psychiatric hospitalization, or strong suicidal thoughts with a plan or intention to act
  • You are currently pregnant
  • You work night shifts or rotating shifts
  • You do not have stable housing
  • You have an untreated medical condition known to affect sleep, such as restless legs syndrome
  • You have a seizure disorder that is not well controlled by treatment
  • You are unable to participate in video calls or complete surveys online

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Shira Maguen, PhD, San Francisco VA Medical Center, San Francisco, CA

Phone: (415) 221-4810

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 May 2023
Est. completion
30 April 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Work and Social Adjustment Scale (WSAS) Change; Work and Social Adjustment Scale (WSAS) Change

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov