Phase 3 Melanoma Trial, Recruiting NCT05789043 Sponsor: Peking University Cancer Hospital & Institute Condition: Melanoma
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Phase 3 Melanoma Trial, Recruiting

NCT05789043
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged 18 or older, of any sex
  • People with acral melanoma (a type of melanoma that typically appears on palms, soles, or under nails) that has been confirmed by laboratory testing and has either come back, cannot be fully removed by surgery, or has spread to other parts of the body (stage III or IV)
  • People who have not yet received any drug-based cancer treatments for this condition
  • People whose cancer can be measured using standard imaging methods, as required by a specific set of medical measurement guidelines
  • People who are able to carry out normal daily activities with little or no limitation (confirm with trial site what level of activity qualifies)
  • People whose organs such as the liver and kidneys are working well enough to participate (confirm specific requirements with trial site)
  • People whose life expectancy is greater than 12 weeks
  • People who have given written consent to participate in the trial

Who may not be able to join:

  • People who are currently receiving or have recently received chemotherapy, radiation therapy, targeted therapy, or immunotherapy
  • People with a known allergy or sensitivity to large protein-based medicines or any ingredient in the trial drug
  • People who have had, or currently have, another type of cancer — except those who have been fully treated for certain skin cancers (basal cell carcinoma) or early-stage cervical cancer
  • People with an active autoimmune disease or a past history of autoimmune disease
  • People with serious heart conditions, including moderate-to-severe heart failure, unstable chest pain, a heart attack within the past year, or certain irregular heart rhythms that require treatment
  • People who received a live vaccine within 4 weeks before the trial's first dose
  • People who are pregnant or currently breastfeeding
  • People considered unsuitable for the trial by the lead doctor or treating physician

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 7 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Jun Guo, Dr, Peking University Cancer Hospital & Institute

Phone: 010-88121122

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Peking University Cancer Hospital & Institute
Registry
ClinicalTrials.gov
Start date
21 March 2023
Est. completion
15 August 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Progression Free Survival, PFS

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov