Phase 3 Endometrial Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are generally healthy and able to carry out normal daily activities with little or no limitations (this is measured on a standard scale called ECOG 0-1)
• You have been diagnosed with endometrial (uterine) cancer that has been confirmed by a lab test, and your cancer has a specific genetic feature called "TP53 wild type" (TP53WT) — this means a certain gene in your cancer is in its normal form
• If your cancer has spread or come back, you must have completed one course of chemotherapy (up to 6 cycles) using specific drugs called taxane and platinum, and your cancer must have responded well to that treatment (shrunk or disappeared), as measured by standard medical guidelines
• Your blood, liver, and kidney functions are at healthy enough levels, checked within the last 14 days

Who may not be able to join:

• Your cancer is a sarcoma or a specific type called small-cell carcinoma with neuroendocrine features
• You have received immunotherapy, cytokine therapy, or any experimental treatment within the last 28 days
• You currently have a surgical drain tube left in your body
• You have a significant heart rhythm problem involving something called a prolonged QTc interval (Grade 2 or higher) — (confirm with trial site)
• You have previously had a major organ transplant (such as a kidney, liver, or heart)
• You have a history of serious bleeding problems, a major bleed, or bleeding in the brain within the last 24 weeks

Important: Always verify eligibility with the trial site directly before applying.