Lung Cancer Trial, Recruiting NCT05802186 Sponsor: Northwestern University Condition: Lung Cancer
Back to Lung Cancer

Lung Cancer Trial, Recruiting

NCT05802186
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People whose scans show findings consistent with lung cancer, or who have a small number of cancer spots in the lung that may have spread from another part of the body (any cancer type may be considered for the spreading cases).
  • For primary lung cancer cases, the lung lesion must have a solid portion making up at least 50% of the total lesion on scans.
  • People whose disease can be measured or assessed on scans according to standard criteria (called RECIST v1.1).
  • People aged 18 years or older.
  • People who are reasonably well and able to carry out daily activities, rated on a standard scale from 0 (fully active) to 2 (up and about more than half of waking hours) (confirm with trial site).
  • People who could potentially become pregnant must have a negative pregnancy test (urine or blood) before joining the trial.
  • People who could potentially become pregnant must agree to use adequate contraception (hormonal methods, barrier methods, or abstinence) from the time of signing consent, throughout the trial, and for 7 days after finishing treatment.
  • People whose partner could become pregnant must agree to use adequate contraception from the time of signing consent, throughout the trial, and for 90 days after finishing treatment.
  • People who are able to understand the trial and are willing to sign a written consent form before joining.

Who may not be able to join:

  • People who have previously had radiation therapy in an area that would overlap with the treatment area planned in this trial.
  • People with primary lung cancer where the lung lesion is entirely or mostly hazy (ground glass opacity) with no solid component on scans.
  • People who are still experiencing significant side effects (rated grade 2 or higher) in the chest area from a previous cancer treatment, such as lung inflammation, airway problems, airway bleeding, or swallowing-tube irritation.
  • People who are currently taking part in another clinical trial using an experimental treatment, or who are receiving certain chemotherapy drugs that damage DNA, at the same time as this trial.
  • People who have another cancer (current or previous) whose disease or treatment could interfere with the safety or results of this trial.
  • People with ongoing or active infections that require treatment through the bloodstream (such as IV antibiotics).
  • People with unstable chest pain (unstable angina).
  • People with stage 3 or more severe idiopathic pulmonary fibrosis (a serious scarring lung condition).
  • People with an irregular heart rhythm (cardiac arrhythmia).
  • People with mental health or personal circumstances that would make it difficult to follow the trial requirements.
  • People with any other illness or condition that the treating doctor feels would affect their safety or the trial's results.
  • People who are pregnant or currently breastfeeding.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Mohamed E Abazeed, MD, PhD, Northwestern University

Phone: 3126951301

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
20 November 2023
Est. completion
1 August 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Local failure free survival (LFS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov