Chronic Kidney Disease Trial, Recruiting NCT05828823 Sponsor: Wake Forest University Health Sciences Condition: Chronic Kidney Disease
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Chronic Kidney Disease Trial, Recruiting

NCT05828823
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

For patients:

  • Adults aged 18 or older
  • People who have recently started, or are expected to start within the next 12 weeks, regular in-centre haemodialysis (a type of kidney dialysis done at a clinic) due to kidney failure
  • People who have had no more than 36 haemodialysis sessions (roughly 12 weeks of treatment) at the time they are approached about the study
  • People whose kidneys are clearing very little urea (a waste product) from the blood — specifically less than 2.0 mL/min (confirm with trial site)
  • People who are still producing at least 500 mL of urine per day (roughly 2 cups)

For caregivers:

  • Adults aged 18 or older
  • People who are the patient's main caregiver, as chosen by the patient
  • People who are a close family member of the patient, such as a spouse, child, sibling, parent, or grandchild
  • People who do not have any known psychiatric or neurological conditions
  • People who are not part of a medical or healthcare team
  • People who are not already caring for another person with a long-term illness
  • People who have not experienced a major life event in the 3 months before joining the study

Who may not be able to join:

For patients:

  • People with certain abnormal blood levels before dialysis — specifically potassium at or above 5.8, sodium at or below 125, or bicarbonate at or below 17 (confirm with trial site for what these numbers mean for eligibility)
  • People who require, or are expected to require, large amounts of fluid removal during dialysis
  • People who are unwilling or unable to follow the study's requirements for any reason
  • People who are pregnant, planning to become pregnant, or currently breastfeeding
  • People whose treating doctor expects them to survive less than 6 months, switch to a different type of dialysis, or transfer to another centre within 6 months

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Mariana Murea, MD, Wake Forest Health Sciences

Phone: 336-716-8671

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
26 February 2024
Est. completion
1 July 2030

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Number of Clinical events of safety

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov