Phase 2 Uveitis Trial, Recruiting NCT05845723 Sponsor: Peking Union Medical College Hospital Condition: Uveitis
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Phase 2 Uveitis Trial, Recruiting

NCT05845723
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are willing to read and sign a consent form before any study activities begin
  • You are between 18 and 65 years old (male or female)
  • You have been diagnosed with Behçet's Disease according to the 2013 international classification criteria
  • You have been confirmed by ultrasound or CT scan to have an abnormal bulging or widening of the main artery in your chest/abdomen (descending aorta) and/or arteries in your limbs
  • Your blood tests show raised levels of inflammation markers (ESR and hs-CRP)

Who may not be able to join:

  • Your blood vessel condition could be caused by another condition such as giant cell arteritis, Buerger's disease, hardening of the arteries, or infection, rather than Behçet's Disease
  • You have other active complications of Behçet's Disease affecting your gut, eyes, or nervous system that need stronger treatment
  • Your aneurysm is so severe that you need emergency surgery (and cases where planned surgery is being considered will be reviewed carefully by specialists)
  • You have serious problems with your liver, kidneys, or blood counts based on recent lab results (confirm with trial site)
  • You have an active infection such as tuberculosis, hepatitis B or C, syphilis, chronic EBV, or another ongoing serious bacterial or viral infection
  • You have a condition that weakens your immune system (either inherited or caused by another illness or treatment)
  • You have or have had a cancer diagnosis
  • You have taken certain immune-suppressing medications (such as Cyclosporin A, Azathioprine, Tacrolimus, Mycophenolate Mofetil, or Cyclophosphamide) in the last month
  • You have recently used certain biological or targeted medicines, with specific waiting periods depending on which drug was used (confirm exact timeframes with trial site)
  • You are currently pregnant, breastfeeding, or planning to become pregnant soon
  • You are unable or unwilling to attend regular check-up visits as required by the study

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 8613581605769

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
1 June 2023
Est. completion
1 June 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

The primary endpoint is the complete response (CR) rate at week 12.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov