Rare Disease Trial, Recruiting NCT05868629 Sponsor: Novartis Pharmaceuticals Condition: Rare Disease
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Rare Disease Trial, Recruiting

NCT05868629
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Your tumor has been tested by a lab and found to have a specific genetic change called a BRAF V600E mutation
  • You have at least one tumor that can be measured on a scan, according to standard medical guidelines
  • You have not previously been treated with the drugs dabrafenib and/or trametinib, OR you took these drugs for a different cancer but stopped taking them more than 1 year ago
  • You are able to provide your scan images for review by a central medical team

Who may not be able to join:

  • You have one of the following cancer types: melanoma, non-small cell lung cancer, anaplastic thyroid cancer, bile tract cancer, glioma, or colorectal cancer (confirm with trial site if you are unsure which category your cancer falls into)
  • You have a medical reason why you should not take dabrafenib and/or trametinib, based on official guidelines in your country

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Novartis Pharmaceuticals, Novartis Pharmaceuticals

Phone: 1-888-669-6682

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
6 February 2024
Est. completion
3 March 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Overall Response Rate (ORR)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov