Phase 2 Endometrial Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with complex atypical endometrial hyperplasia (an abnormal thickening of the uterine lining) or early-stage (grade 1) uterine cancer, confirmed by a tissue biopsy — including those already receiving hormone treatment (progestin) to manage this condition without surgery
• People who have not yet gone through menopause and still have a uterus
• People whose general health and ability to carry out daily activities falls within an acceptable range, as assessed by their doctor (confirm with trial site)
• People aged 18 to 45 years old
• People who are choosing to keep their uterus rather than have it removed — for example, to preserve fertility or for other personal or medical reasons
• People with a body mass index (BMI) of 30 or higher (which falls in the category considered medically obese)
• People who are willing to have a hormonal intrauterine device (IUD) inserted as part of the study, even if they have previously or are currently using progestin hormone treatment
• People who are able to understand the study information and are willing to sign a consent form

Who may not be able to join:

• People currently receiving chemotherapy or radiation therapy for any type of cancer
• People who are pregnant or breastfeeding, or who cannot confirm a negative pregnancy test during the screening period and within 7 days before the IUD is placed
• People who have an active pelvic infection at the time of IUD placement, or who have another medical reason that makes IUD placement unsuitable in their doctor's opinion

Important: Always verify eligibility with the trial site directly before applying.