Leukaemia Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with acute myeloid leukemia (AML), confirmed through bone marrow testing and cell analysis, meeting a specific international diagnostic standard.
• People whose leukemia went into first-time complete remission (meaning no signs of active disease were found) after one or two rounds of initial treatment, and who have since completed at least four rounds of follow-up (consolidation) treatment.
• People aged between 60 and 85 years old.
• People whose liver and kidney function blood test results fall within the acceptable ranges specified by the trial (confirm with trial site for exact values).
• People whose heart pumping function (measured by an echocardiogram, a type of heart ultrasound) shows the heart is pumping at 50% or above.
• People who are reasonably functional in daily life, based on a standard medical scoring scale ranging from fully active to limited self-care (confirm with trial site for exact score requirements).
• People who have given their informed consent, or whose legal representative has done so on their behalf.

Who may not be able to join:

• People whose AML is a specific subtype called acute promyelocytic leukemia, myeloid sarcoma, or leukemia that has transformed from chronic myeloid leukemia.
• People whose leukemia returned after initial treatment and then went into remission again following further treatment.
• People whose leukemia has spread outside the bone marrow, including into the brain or spinal fluid.
• People who have a known allergy to any of the medications used in this trial.
• People who are pregnant, breastfeeding, or of reproductive age and unwilling to use contraception during the trial.
• People whose liver or kidney function results fall outside the acceptable ranges set by the trial.
• People with significant heart conditions, such as uncontrolled or symptomatic irregular heartbeat, heart failure, or a heart attack or serious heart problem within the past six months.
• People who currently have another cancer, unless they finished curative treatment with no known active disease for five or more years, or unless they had certain types of skin cancer or non-invasive cancer that was fully treated with no current signs of disease.
• People who have HIV/AIDS, syphilis, active hepatitis B (with detectable virus in the blood), or hepatitis C.
• People with any other medical condition or active infection that the trial investigators believe could interfere with the study or put the participant at risk.
• People who are unable to understand or follow the trial procedures.
• People who have had major surgery within the four weeks before joining the trial.
• People who have previously received a bone marrow or stem cell transplant from a donor.

Important: Always verify eligibility with the trial site directly before applying.