Phase 2 Lung Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People diagnosed with stage II to IIIB non-small cell lung cancer (a specific type of lung cancer), where doctors have determined that surgery to fully remove the tumour may be possible
• People aged 18 or older at the time of signing the consent form, of any gender, with a good general level of physical functioning, and an expected survival of at least 3 months
• People who have at least one tumour that can be measured on a scan, confirmed within 28 days before treatment starts
• People who have not previously received any cancer treatments such as chemotherapy, radiation therapy, or immunotherapy
• People who are willing to provide a fresh or recent (within 6 months) tumour tissue sample for a specific laboratory test
• People whose major organs (such as heart, liver, and kidneys) are functioning adequately
• Women of reproductive age who agree to use effective contraception during the study and for 6 months after, and who have a negative pregnancy test within 7 days before joining; men who also agree to use effective contraception during the study and for 6 months after it ends
• People who voluntarily agree to participate and sign the consent form

Who may not be able to join:

• People who currently have, or have been diagnosed with, another cancer within the past 5 years
• People whose cancer has a known genetic mutation for which an approved targeted treatment already exists
• People with cirrhosis or active hepatitis (serious liver conditions)
• People with certain heart or brain blood vessel problems
• People who have had a serious active infection within 4 weeks before starting the study, or who have had an unexplained fever above 38°C during the screening period
• People who have had active tuberculosis within the past year
• People with a disease that weakens the immune system
• People with a history of active autoimmune disease (where the immune system attacks the body)
• People who are preparing for or have previously had an organ transplant, or who have had a stem cell transplant within 60 days before starting the study, or who have experienced a significant transplant rejection response
• People who have needed hormone therapy to suppress the immune system and have continued that treatment within 2 weeks before joining
• People who experienced a very severe infection (grade 4 or above) within the past year
• People with serious lung disease (separate from their lung cancer diagnosis) (confirm with trial site)
• People with a history of pituitary or adrenal gland problems
• People with a history of severe mental health conditions
• People with a history of drug abuse, heavy alcohol use, or substance use
• People who have taken part in another clinical drug trial within the past 30 days
• People who have received a live vaccine within 28 days before joining, or who plan to receive one during the study
• People who have received certain traditional Chinese medicines with anti-tumour properties within 2 weeks before starting treatment, as approved by China's national medicines regulator
• People who have had major surgery within 4 weeks before starting treatment
• People with other serious medical conditions or significant laboratory test abnormalities that, in the opinion of the trial doctors, could affect safety or the study results
• People who are unlikely to be able to follow the trial requirements consistently

Important: Always verify eligibility with the trial site directly before applying.