Head and Neck Cancer Trial, Recruiting NCT05919290 Sponsor: University Health Network, Toronto Condition: Head and Neck Cancer
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Head and Neck Cancer Trial, Recruiting

NCT05919290
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

For people with cancer:

  • Adults aged 18 years or older
  • People who have been diagnosed with a specific type of head and neck cancer called squamous cell carcinoma, confirmed through a tissue test
  • People whose cancer (in the primary area or nearby lymph nodes) measures more than 3cm
  • People who are in reasonably good general health, based on a standard medical scale (ECOG score of 0–2)
  • People who are planned to have surgery or radiation therapy (with or without chemotherapy) with the aim of curing the cancer
  • People who are willing to have more than one MRI scan during the study
  • People who are able to understand and sign a written consent form
  • People whose kidneys are functioning at an adequate level, based on a specific blood test result
  • People who are able to lie flat on their back comfortably for up to one hour

For healthy volunteers:

  • Adults aged 18 years or older
  • People who are willing to have more than one MRI scan during the study
  • People who are able to understand and sign a written consent form

Who may not be able to join:

For people with cancer:

  • People who, in the opinion of the study doctor, have other serious illness that makes participation unsuitable
  • People for whom having repeated MRI scans is medically not appropriate
  • People who have had another solid-organ cancer treated within the last 5 years
  • People who are pregnant
  • People with a history of significant breathing or airway problems
  • People who have had an allergic reaction to gadolinium contrast dye (a substance used in some MRI scans)

For healthy volunteers:

  • People who are unwilling to sign a consent form
  • People for whom having an MRI scan is medically not appropriate
  • People with a significant underlying lung or breathing condition

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Andrew McPartlin, MD, Radiation Oncologist

Phone: 416-946-4501

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
26 July 2023
Est. completion
1 July 2029

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Change in hypoxia level during radiotherapy as assessed by fMRI (functional magnetic resonance imaging); Change in tumour tissue and microenvironment during radiotherapy as assessed by fMRI

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov