Phase 2 Leukaemia Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 15 to 65 years old
- People diagnosed with a type of blood cancer called CD22+ B-cell acute lymphoblastic leukaemia (B-ALL), based on 2023 NCCN diagnostic standards
- People with CD22+ B-ALL whose cancer has shown signs of returning (detected by a sensitive test called MRD) after a bone marrow/stem cell transplant — or, for those with a specific type called Ph+ ALL, people whose cancer did not respond to one or more second-generation targeted therapies (TKIs)
- People with a general health and activity level rated below a certain threshold (ECOG score of less than 3, meaning able to carry out some daily activities) (confirm with trial site)
- People expected to survive at least 3 months
- People without serious heart, lung, liver, or kidney disease
- People who are able to understand the trial and agree to take part voluntarily
Who may not be able to join:
- People with a known allergy to the study drug or chemically similar drugs
- People who are pregnant, breastfeeding, or of childbearing age who are unwilling to use effective contraception during the trial
- People who currently have an active infection
- People who are currently experiencing active bleeding
- People who have had a blood clot, blockage in a blood vessel, brain bleed, or similar condition within the past year
- People with a mental health condition or other circumstances that would prevent them from giving informed consent or following the study requirements
- People with significantly abnormal liver function results or abnormal kidney function results on blood tests (confirm specific values with trial site)
- People with a significant history of certain heart conditions, including abnormal heart rhythm measurements, irregular heartbeat, a particular type of heart block, a heart attack within the past year, heart failure, or coronary heart disease requiring medication
- People who have had surgery on a major organ within the past six weeks
- People with a history of drug abuse or long-term heavy alcohol use that could affect the trial results
- People who have had an organ transplant (other than a bone marrow transplant)
- People considered unsuitable for the trial by the treating doctor or investigator
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 0086-0512-67781139
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
the rate of MRD-
Can't join this trial?
Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.