Osteoporosis Trial, Recruiting NCT05946278 Sponsor: University of Colorado, Denver Condition: Osteoporosis
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Osteoporosis Trial, Recruiting

NCT05946278
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults between 18 and 85 years old who are having a major spinal surgery, such as a fusion connecting many levels of the spine down to the pelvis, a surgery that removes and reshapes bone in the spine, or any major spinal correction surgery where the surgeon expects to remove and discard a large amount of bone material.
  • People who are willing and able to give their informed consent to take part.

Who may not be able to join:

  • People with end stage kidney failure.
  • People with any history of cancer.
  • People who have relied on a wheelchair for 70% or more of their movement for longer than 12 months.
  • People who have complete paralysis of both arms and legs, or both legs, due to a spinal cord injury.
  • People who are currently taking medication to treat epilepsy.
  • People with confirmed Marfan syndrome, osteogenesis imperfecta (brittle bone disease), or other inherited conditions known to affect how bones form.
  • People who have been taking steroid medications (such as prednisone or cortisone) continuously for more than 3 months, or for a total of more than 6 months over their lifetime.
  • People who currently have, or are suspected to have, an infection involving spinal hardware or implants.
  • People who are HIV-positive or Hepatitis C-positive, or who are currently taking antiviral medications.
  • People who have had gastric bypass surgery, or who have lost more than 100 pounds in weight.
  • People with a condition causing overactive parathyroid glands (a gland that controls calcium in the body), whether caused by the glands themselves or by another condition.
  • People with Paget's disease of bone (a condition that disrupts normal bone rebuilding).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Cheryl L Ackert-Bicknell, PhD, University of Colorado, Denver

Phone: 3037246623

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 April 2024
Est. completion
30 August 2030

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Gene and transcript quantification; Genotypes

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov