Osteoporosis

**Who might be able to join this trial:** **Group 1 (main group):** - You are between 40 and 65 years old - You are a woman who has had breast surgery and still has your uterus (you have not had a hysterectomy) - You have been taking aromatase inhibitor medication (a type of hormone-blocking drug used after breast can...

Who might be able to join this trial: - Women aged 40 to 64 who are generally healthy, have gone through menopause, and are looking for treatment to help with menopause symptoms - Women who have not had a period for at least 12 months on their own, OR have not had a period for at least 6 months and have hormone test re...

**Who might be able to join this trial:** - You are willing and able to give written consent to participate - You are an adult aged 18 or older who is living with HIV - You have been on a stable HIV treatment regimen that includes two specific medications (tenofovir/TDF and a type of drug called a boosted protease inhi...

**Who might be able to join this trial:** - You are a woman who has gone through menopause - Your bone density scan (at the hip) shows a T-score of -2.50 or lower, AND you have had at least one moderate or severe spinal (vertebral) fracture, OR at least two mild spinal fractures - Your bone density scan (at the hip) sh...

**Who might be able to join this trial:** - Women aged 50 or older, or men aged 70 or older - People who have been in the Intensive Care Unit (ICU) for at least 2 full days and are not expected to leave the ICU on that second day - People who have needed a significant level of ICU support — such as breathing machines,...

Who might be able to join this trial: - You must be aged 18 or older and living in Australia. Who may not be able to join: - There are no stated exclusion criteria for this trial. Important: Always verify eligibility with the trial site directly before applying.

**Who might be able to join this trial:** - You must be at least 1 day old (this trial is open to all ages, including newborns, children, and adults) - You have a known or suspected bone disease, shown by things like a fracture, unusual bone findings on an X-ray, CT scan, MRI, or bone density test, or a personal or fam...

Who might be able to join this trial: - People who are older than 20 years of age - People who have had an incomplete atypical femur fracture (a specific type of thigh bone stress fracture) that meets the official diagnostic guidelines set by an international bone health expert group (ASBMR), or a low-force or no-force...

"Who might be able to join this trial: - You are 45 years of age or older - You are a man or woman living in Quebec who has had, or is currently having, a specific type of unusual thigh bone (femur) fracture called an atypical femoral fracture (AFF) — this includes both complete breaks and partial cracks, as identified...

**Who might be able to join this trial:** - People aged 50 or older who also meet at least one of the following conditions: - People who have recently had a hip fracture and are being treated in an orthopaedic ward - People in a geriatric ward where an X-ray has newly identified a spinal (vertebral) fracture, or peopl...

**Who might be able to join this trial:** - You have been diagnosed with a long-term inflammatory rheumatic disease or psoriasis (or, for the control group, you have not been diagnosed with these conditions) - You are currently taking, have previously taken, or are expected to start a long-term steroid (glucocorticoid)...

Who might be able to join this trial: - People who are permanent residents of the relevant area. - Women between the ages of 45 and 79, or men between the ages of 50 and 79. Who may not be able to join: - People with severe mental health conditions, serious physical illnesses, or acute infectious diseases that would m...

Who might be able to join this trial: - You have been diagnosed with osteoporosis (a condition that weakens bones) - You have had a hip fracture due to osteoporosis (specifically a break at the top of the thigh bone, either at the neck or the trochanter region) - You are willing and able to take part in the study and h...

Who might be able to join this trial: - You are between 30 and 90 years old - You are attending a health check-up and are having a low-dose CT scan of your chest Who may not be able to join: - You are pregnant - You have a metal implant in the area of your body being scanned by the CT machine Important: Always verify...

Who might be able to join this trial: - You have been diagnosed with osteoporosis (a condition that causes weak and brittle bones) Who may not be able to join: - You do not have osteoporosis - You are allergic to the drugs being used in this trial (confirm with trial site) - You do not wish to take part in the researc...

Who might be able to join this trial: - People who have been diagnosed with Cystic Fibrosis (CF), confirmed by a sweat test or genetic analysis - People (and their parents or legal guardians, if applicable) who are able to read and write in English Who may not be able to join: - People who do not have a Cystic Fibrosi...

**Who might be able to join this trial:** - Men and women aged 50 or older who have been diagnosed with osteoporosis (weakened bones) - People with either high blood pressure or normal blood pressure are welcome - People whose bone density scan (DEXA scan) shows a T-score of -2.5 or lower, meaning their bone density is...

**Who might be able to join this trial:** - People who have had a hip (femoral neck) fracture that likely happened due to osteoporosis — meaning it occurred with little or no significant injury — and who are being treated with a hip replacement surgery. - People who are mentally able to understand the study and have si...

**Who might be able to join this trial:** - People who have cancer or osteoporosis and are being treated with medication that slows bone loss (called antiresorptive treatment) - People who are willing and able to attend all the planned check-ups and assessments required by the trial - People who are expected to live fo...

Who might be able to join this trial: - You must be 18 years of age or older - You are having your first hip replacement surgery (not a revision or repeat procedure) - You are willing and able to sign a consent form agreeing to take part - You are already scheduled to have a routine CT scan before your surgery as part...

**Who might be able to join this trial:** - The person is a woman who has gone through menopause, has not had a period for at least one year, and is between 65 and 91 years old. - The person has had a hip fracture caused by a minor incident (such as a low-level fall) and is scheduled to have surgery to repair that hip...

Who might be able to join this trial: - Adults aged 18 or older who have been diagnosed with osteoporosis. - People who are willing and able to provide written consent to participate. Who may not be able to join: - People who have not been diagnosed with osteoporosis. - People who are not willing or able to provide wr...

**Who might be able to join this trial:** - You are a woman who has gone through menopause and has not had a period for at least one year - Your hip bone scan (DXA) shows a T-score of -2.5 or lower, meaning you have significant bone loss from osteoporosis in your hip - At least one of your hips has never had surgery or...

Who might be able to join this trial: - Women aged 50 or older who have been diagnosed with postmenopausal osteoporosis (with or without a fracture) and for whom a doctor has decided to start treatment with bone-strengthening medications, such as bisphosphonates, raloxifene, teriparatide, denosumab, or romosozumab, tak...

Who might be able to join this trial: - You must be older than 18 years of age - You must have low levels of plaque and gum bleeding (less than 30% when measured by a dentist) - You must have a specific anatomical feature where the sinus cavity dips into the area between the roots of your upper first molar (confirm wit...

Who might be able to join this trial: - People aged 65 years or older Who may not be able to join: - People who have a known blood condition, such as myelodysplasia, leukemia, or cancer - People who are not able to provide written consent to participate in the trial Important: Always verify eligibility with the trial...

**Who might be able to join this trial:** - People aged 60 or older who are veterans - People who live in the Denver Metro Area - People who are generally active, such as those who regularly walk or cycle for recreation **Who may not be able to join:** - People whose kidneys are not functioning well enough (based on a...

Who might be able to join this trial: - Women who have gone through menopause and are between 50 and 65 years old - People whose bone density scan results fall in a range that suggests lower than normal bone density but not yet full osteoporosis (a T-score between -1 and -3) - People who have not had any broken bones c...

Who might be able to join this trial: - Women aged over 45 years who have gone through menopause - People who meet the menopause criteria in one of two ways: either more than 36 months have passed since their last natural period, or more than 36 months have passed since a hysterectomy, with a specific hormone level (FS...

**Who might be able to join this trial:** **Main Study:** - You have been diagnosed with cystic fibrosis (CF) - You are female and have had at least one menstrual period - You are willing to stay on the same type of estrogen supplement (or none at all) for the whole study **Feasibility Sub-Study (in addition to the a...

Who might be able to join this trial: - People with osteoarthritis who are having joint replacement, bone realignment, or joint fusion surgery on any joint, including the hip, knee, shoulder, wrist, elbow, or ankle. - People with a broken hip bone who are having a partial or full hip replacement, or another type of sur...

**Who might be able to join this trial:** - People who live independently in their own home or community (not in a care facility) - People with a body mass index (BMI) over 30, or a BMI between 25 and 30 with at least one additional health risk factor (confirm with trial site for what counts as a risk factor) - People...

**Who might be able to join this trial:** - People of any gender who are 55 years of age or older and have been diagnosed with osteopenia (a condition where bone density is lower than normal but not low enough to be called osteoporosis, defined by a T-score below 0.0 but higher than -2.5 on a bone density scan) **Who...

Who might be able to join this trial: - You are over 50 years old - You have been diagnosed with osteoporosis confirmed by a DEXA scan (a type of bone density scan) Who may not be able to join: - You have previously been diagnosed with osteoporosis before this trial - You have previously received any treatment for ost...

**Who might be able to join this trial:** - People who have recently had a brittle (fragility) hip fracture - People who have recently had a brittle (fragility) spinal fracture - People who have recently had a brittle (fragility) fracture at another location in the body, and/or have a bone density scan result below a c...

Who might be able to join this trial: - People aged 75 years or older who have had a hip fracture Who may not be able to join: - People who do not wish to receive treatment - People for whom a different osteoporosis treatment has been recommended by their doctor - People who do not live in the area covered by the admi...

**Who might be able to join this trial:** - You are 40 years old or older and have had a bone density scan (a type of X-ray called a DEXA scan) done at the health management center of the hospital running this trial - You are able to make your own decisions and are willing to take part, and you agree to sign a consent...

**Who might be able to join this trial:** **For all participants:** - Adults (male or female) - People who are able to give their consent to take part in research - People who are enrolled in a French Social Security health plan **For the finger osteoarthritis group:** - People who are seen as outpatients in the Rheu...

Who might be able to join this trial: - Adults between 18 and 85 years old who are having a major spinal surgery, such as a fusion connecting many levels of the spine down to the pelvis, a surgery that removes and reshapes bone in the spine, or any major spinal correction surgery where the surgeon expects to remove and...

**Who might be able to join this trial:** - People who have been diagnosed with cognitive impairment, confirmed through clinical assessment, brain imaging, or lab tests - People who are willing to start treatment for their cognitive impairment - Women who are either older than 55 years, or under 55 years and have not h...

**Who might be able to join this trial:** - Women who have been through menopause for at least two years - Women whose bone density scan shows a T-score below -2.5 at the lower spine, hip, or upper thigh bone (indicating osteoporosis) - Women who have had a bone fracture in the last 3 years at the spine, hip, pelvis, s...

**Who might be able to join this trial:** - You are a man or woman aged 65 or older who is able to walk (even with assistance) - You live in a nursing home, assisted living facility, or senior community - You have been diagnosed with osteoporosis (weak or thinning bones), which may have been confirmed by a bone density...

**Who might be able to join this trial:** - People who have lived in the same city as the hospital for at least six months - People aged 50 years or older who are currently in hospital with a fracture - People who have never had a fracture before - People who have never been diagnosed with osteoporosis before being adm...

**Who might be able to join this trial:** - Women who have gone through menopause, have been diagnosed with severe osteoporosis, and have recently completed a full course of treatment with either romosozumab or teriparatide (two specific bone-strengthening medications) **Who may not be able to join:** - People who hav...

**Who might be able to join this trial:** - You are between 19 and 30 years old - You get less than 1,000 mg of calcium per day from your diet - You live in or around Saskatoon, Saskatchewan, Canada **Who may not be able to join:** - You get more than 800 mg of calcium per day in total from food and supplements combin...

**Who might be able to join this trial:** - Women of Caucasian background who have gone through menopause and live in the Emilia-Romagna region - Women who reached menopause at age 45 or older **Who may not be able to join:** - People who have or have had cancer (tumours) - People who do not live independently (for ex...

Who might be able to join this trial: - People who are already scheduled to have a lumbar and/or femoral DXA scan (a type of bone density scan) - People who are female - People aged between 30 and 80 years old (for the repeatability part of the study), or between 50 and 70 years old (for the accuracy part of the study)...

**Who might be able to join this trial:** - You have been diagnosed with broken bones in your spine (in the chest or lower back area) caused by osteoporosis (a condition that weakens bones), based on the 2022 guidelines for osteoporotic fractures - A scan called an MRI has clearly shown signs of a fresh/recent fracture...

Who might be able to join this trial: - People aged 60 years or older. - People who have given written consent to take part and are available and willing to follow the study requirements for the entire study period. - People whose bone density scan (DXA) of the hip and spine shows a T-score above -2.5 (meaning bone den...

**Who might be able to join this trial:** - You have been diagnosed with an inflammatory rheumatic joint disease (a condition where the immune system causes painful swelling in the joints, such as rheumatoid arthritis) - You are about to start a disease-modifying treatment (medication that slows down the disease) with...

**Who might be able to join this trial:** *For older women:* - You have been diagnosed with osteoporosis, either told by a doctor or recorded in your medical records - You are aged 70 years or older - You live independently in your own home in the community (not in a care home) *For healthcare professionals:* - You c...

Who might be able to join this trial: - Participants must be male. - Participants must be aged 50 years or older. - Participants must have clinical and medical history information available from a CT scan of the abdomen and chest. - Participants must be willing and able to sign a consent form agreeing to take part in t...

Who might be able to join this trial: - Both men and women of any background or ethnicity are welcome to participate. - You must be 18 years old or older. - You are already scheduled to have a CT scan of your lower back or abdomen for any medical reason (no specific condition is required). - The CT scan must be able to...

**Who might be able to join this trial:** - You are 50 years of age or older (there is no upper age limit) - You had a bone fracture in the last 12 months that happened from a minor injury (such as a simple fall) affecting the hip, thigh bone, pelvis, spine, upper arm, or wrist - You have a regular family doctor or pri...

Who might be able to join this trial: - People who have gone through menopause - People who have been attending regular outpatient appointments for osteoporosis for at least one year Who may not be able to join: - People with bone, joint, muscle, or nerve conditions that could make it difficult to take part in exercis...

**Who might be able to join this trial:** - You have had a CT scan (covering the chest, abdomen, pelvis, and spine) taken at the hospital's radiology department within one month before or after your inpatient stay — this applies to the sarcopenia (muscle loss) part of the study. - You have had both a CT scan of the ch...

Who might be able to join this trial: - Postmenopausal women who have had a hip fracture (specifically a type called a subcapital femoral neck fracture) caused by osteoporosis (Arm 1) - Postmenopausal women who have hip osteoarthritis and are scheduled to have a total hip replacement surgery (Arm 2) Who may not be abl...

**Who might be able to join this trial:** **For patients (people being studied for bone health concerns):** - Men or women receiving care at Saint-Etienne University Hospital who are at risk of osteoporosis (weak bones) - People who have previously broken a bone due to weak or fragile bones - People who have been reco...

Who might be able to join this trial: - People who are generally healthy and attending regular check-ups or outpatient visits for preventive health screening - People who have been diagnosed with low bone density (osteopenia) and have had a bone density scan (DXA) done - People who have been diagnosed with osteoporosis...

Who might be able to join this trial: - Women who are 45 years of age or older - Women who have gone through menopause - Women who have been diagnosed with osteoporosis and are considered at high risk of bone fractures Who may not be able to join: - Women who have previously used treatments that significantly affect b...

"Who might be able to join this trial: - People who are women Who may not be able to join: - People who have been diagnosed with osteoporosis (a condition that causes bones to become weak and brittle) Important: Always verify eligibility with the trial site directly before applying."

Who might be able to join this trial: - Adults between 18 and 35 years old - Female - Willing to participate using a pseudonym (a false name to protect identity) - Currently serving as an occupational (professional) soldier - Free from any ongoing or current muscle or joint injuries Who may not be able to join: - Peop...

**Who might be able to join this trial:** - People aged 65 years or older, of any gender - People who have been diagnosed with both sarcopenia (low muscle mass and either low grip strength or poor physical performance, measured using specific tests and a body scan) and osteoporosis (low bone density, with a specific sc...

Who might be able to join this trial: - You are 18 years of age or older (male or female) - You are willing to take part and have agreed to allow your X-ray images and health information to be used for research - You have had X-ray images of both your hip and spine, as well as a bone density scan (DEXA scan) - Your med...

Who might be able to join this trial: - Women who have gone through menopause and have had a bone density scan (DXA) done within the last 6 months. - Women whose bone density scan results show either normal bone density (T-scores of -1 or above at the hip and spine) for the control group, or osteoporosis (T-scores of -...

Who might be able to join this trial: - You are over 60 years old - You have one or more long-term, non-infectious health conditions (such as diabetes or high blood pressure) that are being treated with medication - You are currently taking a medication combination called BIC/TAF/FTC (also known as Biktarvy) at the tim...

Who might be able to join this trial: - Women who have gone through menopause and are between 60 and 90 years old - People whose bone density scan results show bones that are weak enough to be considered osteoporosis (a T-score below -2.5 at the spine or hip), but not lower than -4.0 at either site - People who either...

Who might be able to join this trial: - You are 65 years old or older - You were living in the community (such as in your own home or an apartment) when you broke a bone - You are staying at a participating skilled nursing facility (a short-term rehabilitation center) to recover from a broken bone in your lower body, i...

**Who might be able to join this trial:** - You are a man or woman aged 65 or older with either Type 1 or Type 2 diabetes - You live in your own home - You were diagnosed with diabetes at least one year ago - You are willing and able to sign a consent form to take part in the study - You have some previous experience w...

**Who might be able to join this trial:** - You are a woman who has gone through menopause and has been diagnosed with osteoporosis (thinning of the bones) - You have been taking a medication called denosumab for at least 2 years, and your doctor has decided it is time to stop it because your treatment has gone well (n...

Who might be able to join this trial: - You are 50 years old or older and have been diagnosed with painful spinal fractures caused by osteoporosis (brittle bones), located in the middle or lower back area. - You have tenderness or pain when the affected area of your spine is touched. - Your fracture has been confirmed...

Who might be able to join this trial: - People who have been diagnosed with a neurological disorder (a condition affecting the brain, spinal cord, or nerves) - Healthy people with no medical conditions who can take part as a comparison group (controls) Who may not be able to join: - People who are unable to fully unde...

Who might be able to join this trial: - Women aged 50 to 80 years old who are able to walk around freely - Women whose bone density scan (a type of scan called a DXA) shows a T-score between -4.0 and -2.5 at the spine, hip neck, or total hip — meaning bone density is low but not severely low - Women who have at least o...

Who might be able to join this trial: - People who have been diagnosed with rheumatoid arthritis Who may not be able to join: - People who have a systemic (whole-body) disease that affects bone metabolism, or who are taking medications that affect bone metabolism - People who have metal implants or materials in their...

Who might be able to join this trial: - You must be over 18 years old - You are receiving a liver transplant, for any medical reason - You are able to have a bone density scan carried out - You are able to have blood tests or other checks related to bone and mineral health carried out - You are willing and able to give...

Who might be able to join this trial: - People who have been diagnosed with primary osteopenia (low bone density) or osteoporosis (weak, brittle bones), with or without sarcopenia (low muscle mass and strength), based on current medical guidelines and standard diagnostic criteria. Who may not be able to join: - People...

Who might be able to join this trial: - People who have been diagnosed with a lumbar disc herniation (a slipped disc in the lower back) and osteoporosis (weakened, brittle bones), based on their medical records and clinical assessment. - Female patients aged 45 or older, or male patients aged 50 or older. - People who...

Who might be able to join this trial: - You must be female - You must be postmenopausal - You must currently be taking a bone medication called Alendronate - You have been taking Alendronate for more than 3 years AND have not had any bone fractures, OR you have been taking Alendronate for more than 5 years AND your mos...

**Who might be able to join this trial:** - Adults between 40 and 75 years old who have been diagnosed with low bone density or bone loss (called osteopenia or osteoporosis), confirmed by a bone scan called a DXA scan, with a T-score of -1.0 or lower - People with stable eating habits who are willing to keep their cur...

**Who might be able to join this trial:** - People who have been diagnosed with Rheumatoid Arthritis (RA) based on recognised international diagnostic guidelines (the ACR/EULAR 2010 criteria) - People who are female or male and are over the age of 50 - People who have the mental and physical ability to complete the stu...

**Who might be able to join this trial:** - People aged 65 or older who have lived in the local area for more than 6 months within the past year **Who may not be able to join:** - People who have a diagnosed cognitive impairment (such as dementia) or a mental illness **Important: Always verify eligibility with the tr...

**Who might be able to join this trial:** - You are a woman who has gone through menopause and are between 50 and 90 years old - Your bone density scan shows a T-score of -3.0 or lower in at least one bone in your lower spine (meaning significantly low bone density) - You are physically and mentally able to understand...

Who might be able to join this trial: - Women who have gone through menopause (there is no upper or lower age limit for women) - Men who are 50 years of age or older Who may not be able to join: - People who are currently taking medications that may affect bone health - People whose health conditions may make it unsaf...

Who might be able to join this trial: - Women between the ages of 55 and 75 years old - Women who have been diagnosed with osteoporosis based on a bone density scan (DXA) done within the last six months - Women in a similar age range who have not been diagnosed with osteoporosis and would participate as healthy compari...

Who might be able to join this trial: - Women who have gone through menopause, meaning their periods stopped at least 12 months ago - Women between 50 and 60 years old - Women with a body mass index (BMI) — a measure of body weight relative to height — below 30 - Women with a vitamin D level that is low but not severel...

**Who might be able to join this trial:** - Women aged 50 or older who have gone through menopause (defined as having no menstrual periods for one full year), or men aged over 60. - People who have been diagnosed with one or more new, painful spine fractures in the mid-to-lower back region (from the upper back down to...

**Who might be able to join this trial:** **For people with osteoporosis:** - Women aged 50 or older who have been diagnosed with postmenopausal osteoporosis by a rheumatologist, whether or not they have had a fracture - People who are able to give their consent to take part in the research - People who are affiliated...

**Who might be able to join this trial:** - People who agree to take part in the study and sign a consent form. - Women who have gone through menopause, are able to walk without assistance, and are between 50 and 85 years old (inclusive). - People whose bone density scan results in the lower back or hip area show a T-...

**Who might be able to join this trial:** - People who are aged 18 to 100 years old - People whose body mass index (a measure of body weight relative to height) falls between 16.0 and 60 kg/m² **Who may not be able to join:** - People younger than 18 or older than 100 years old - People whose body mass index is below...

Who might be able to join this trial: - Women who have been diagnosed with postmenopausal osteoporosis - Women who have been prescribed a monthly or weekly oral bisphosphonate (a type of bone-strengthening medication) along with a daily calcium and vitamin D supplement (in sachet or chewable tablet form), with this tre...

Who might be able to join this trial: - You are between 44 and 55 years old - Your body mass index (a measure of body weight relative to height) is below 35, meaning you are not severely overweight - You are considered generally healthy, based on a health questionnaire, a physical check-up with a nurse practitioner, an...

**Who might be able to join this trial:** *Hemodialysis (HD) group:* - You have been receiving kidney dialysis (hemodialysis) for at least 12 months and are between 20 and 70 years old, and you are willing to sign a consent form. *Kidney Transplant (KTR) group:* - You received a kidney transplant at least 12 months a...

**Who might be able to join this trial:** **Group 1 (Mast Cell Activation)** — People who meet the criteria for either of the following: - People who have had a documented severe allergic reaction (anaphylaxis) to insect stings (such as bees or wasps) that affected the heart or blood circulation, OR a severe allergic...

Who might be able to join this trial: - Adults aged 18 years or older - People who have already had a routine abdominal CT scan done without contrast dye - People whose CT scan images included the upper part of the thigh bone (the area near the hip joint) - People whose CT scan was done for a reason unrelated to bones...

Who might be able to join this trial: - People who are female or male, aged between 21 and 55 years (inclusive) - People who have given written agreement to take part in the trial Who may not be able to join: - People who have conditions that would interfere with bone scanning measurements, such as fractures, metal im...

Who might be able to join this trial: - People who have had a hip fracture, regardless of their age - People who are cognitively well-functioning (thinking and memory are not impaired) - People who are able to understand what the study involves and agree to take part - People who can speak and understand Danish - Peopl...

**Who might be able to join this trial:** - You are a woman between 60 and 75 years old, of any ethnicity. - A bone density scan (DXA scan) done within the last 6 months shows your bone strength is lower than normal but not yet at the level of osteoporosis (a T-score between lower than -1.0 and higher than -2.5). - Yo...

Who might be able to join this trial: - You have had an ischemic stroke (caused by a blockage) or a hemorrhagic stroke (caused by bleeding in the brain) - Either between 1 week and 6 months have passed since your stroke, or more than 1 year has passed since your stroke - You are between 55 and 85 years old Who may not...

**Who might be able to join this trial:** - Women who have gone through menopause and are between 50 and 75 years old - People who have been diagnosed with osteoporosis based on a bone density scan result (called a DEXA scan), with a T-score of -2.5 or lower - People who have been in menopause for at least one year - P...

Who might be able to join this trial: - People who are female - People who are 18 years of age or older - People who are scheduled to have surgery for breast cancer affecting one breast only Who may not be able to join: - People who would not be able to attend follow-up visits as required by the trial - People who hav...

**Who might be able to join this trial:** - Women who have gone through menopause and have not had a menstrual period for at least one year - Women who are older than 50 years of age - People who have been diagnosed with primary osteoporosis (bone loss not caused by another condition or medication) - People who are not...

Who might be able to join this trial: - You must be postmenopausal (your periods have permanently stopped). - For the **osteoporosis group**: you must have been diagnosed with osteoporosis in the hip area, shown by specific bone density scan scores at the femoral neck or total hip (T-score of -2.5 or lower). - For the...

**Who might be able to join this trial:** - Women who are older than 40 and up to 65 years of age at the screening visit - People with a body mass index (a measure of weight relative to height) between 18 and 35 - People who have confirmed menopause, either by having had no periods naturally for 12 or more consecutive...

**Who might be able to join this trial:** - You are a white/Caucasian woman between 35 and 70 years old - You have been diagnosed with breast cancer and are being treated with certain hormone-blocking medications (aromatase inhibitors, or tamoxifen combined with hormone-suppressing injections, or both) that were starte...

Who might be able to join this trial: - Women who have been through menopause for at least two years - Women aged 40 years or older - Women whose bone density scan results show a T-score of -2.0 or higher (meaning bone density is not severely low) - Women who have at least two lower spine bones that can be measured by...

Who might be able to join this trial: - Women who have gone through menopause, are between 50 and 85 years old, and have had a broken bone related to osteoporosis or low bone density (osteopenia). - Men who are between 50 and 85 years old and have had a broken bone related to osteoporosis or low bone density (osteopeni...

Who might be able to join this trial: - Women who have gone through menopause and are over 50 years of age, with a bone density scan result showing osteoporosis (a T-score of -2.5 or lower at the spine, hip, or femoral neck) - Women who have never taken any medication for osteoporosis, whether by injection or by mouth...

Who might be able to join this trial: - People who are over the age of 50, including men and women who have gone through menopause - People who have had a spinal bone fracture within the last two years - People who are willing to take part in 12 online rehabilitation sessions over 10 weeks - People who have access to t...

**Who might be able to join this trial:** - Adults aged 18 or older with normal bone density, confirmed by a special bone scan called a DXA scan, and no history of bone diseases, major organ problems, or long-term inflammatory or immune conditions (this group serves as healthy comparison participants) - Adults aged 18...

Who might be able to join this trial: - You are between 21 and 85 years old - You have a single spinal fracture caused by compression (not a burst or twisting injury) located in the mid or lower back area of the spine - Your fracture is either less than 6 weeks old, or imaging shows it may still be possible to correct...

Who might be able to join this trial: - You are a doctor based in the Alsace region who treats older patients with osteoporosis (a condition that weakens bones) - You have had the chance to use a practical guide about osteoporosis at some point Who may not be able to join: - You are a doctor who has never had the oppo...

Who might be able to join this trial: - People who are 22 years of age or older - People who have been approved by their doctor to have a CT- or CBCT-guided procedure on the pelvis or spine (not including the neck area) performed under general anesthesia - People who have signed a consent form that has been approved by...

**Who might be able to join this trial:** - People who have been diagnosed with osteoporosis, confirmed by a bone density scan (DEXA scan) showing a T-score of -2.5 or lower - People between the ages of 65 and 75 years old - People with a body mass index (BMI) between 25 and 29.9 (considered in the overweight range) -...

**Who might be able to join this trial:** - Women who have had breast cancer and are between 40 and 60 years old - People whose breast cancer was confirmed through laboratory testing and was at an early to middle stage (stage I, II, or III) - People who have been taking a type of hormone therapy called aromatase inhib...

**Who might be able to join this trial:** - Women aged 45 to 70 years who have gone through menopause, with their last menstrual period no more than 10 years ago - People who have not used hormone replacement therapy for at least one year before the study begins - People who currently exercise less than 7 hours per we...

Who might be able to join this trial: - You are a woman or a man - You are over 50 years old - You have been diagnosed with osteoporosis or low bone density (osteopenia), either through an official diagnosis in your medical records or because you are currently taking or have previously taken medication for osteoporosis...

Who might be able to join this trial: - A parent or legal guardian (or the patient themselves if an adult) has given written consent to participate - The patient is between 5 and 18 years of age - People of any sex or ethnicity may be eligible - The patient has a known medical condition that negatively affects bone hea...

Who might be able to join this trial: - Women who are 65 years of age or older - Men who are 70 years of age or older Who may not be able to join: - People who have problems with thinking, memory, or mental processing (cognitive dysfunction) - People who have been diagnosed with dementia - People who have a psychiatri...

**Who might be able to join this trial:** - You are 50 years of age or older at the time your chest X-ray was taken - You have had a chest X-ray (taken from the front, called a PA view) and a bone density scan (called a DXA scan) performed within 6 months of each other - Both your chest X-ray and bone density scan wer...

**Who might be able to join this trial:** - You are 18 years old or older - Both men and women are welcome to participate - You have already had relevant bone imaging done, such as an X-ray, CT scan (without contrast), or MRI (without contrast) - The bones in the area being studied have a normal structure, with no birt...

**Who might be able to join this trial:** - People who have signed a consent form and are willing to take part and complete the study questionnaires - Pregnant women who are between 35 and 41 weeks along at the time of joining the study - Women carrying one baby or twins (including both types of twin pregnancies) - Wo...

Who might be able to join this trial: - Women aged 18 or older who have normal AMH levels (a hormone that indicates ovarian reserve) - People who are able to give their informed consent to participate Who may not be able to join: - People who have previously had ovarian tissue removed and transplanted back into their...

**Who might be able to join this trial:** - You are a woman who can move around independently, and you are between 45 and 80 years old - Your periods stopped naturally at least 3 years ago, OR you had surgery to remove your ovaries at least 3 years ago (the surgery must have been done after age 40); if your menopause...

Who might be able to join this trial: - People aged 65 years or older at the time of screening. - People with a Body Mass Index (a measure of body weight relative to height) below 30. - People identified as "pre-frail" based on a recognised frailty assessment, meaning they meet 1 or 2 out of 5 specific signs of physica...

Who might be able to join this trial: - You must be female - You must have gone through menopause (your periods have stopped) - You must have been diagnosed with osteoporosis (weak or thinning bones) based on a bone density scan - You must be eating a normal amount of calcium in your diet - You must be taking a vitamin...

Who might be able to join this trial: - You are between 40 and 80 years old - You have been identified as being at higher risk for osteoporosis based on a specific screening tool that uses your age and weight (confirm with trial site) - You have had a chest X-ray taken within the past year Who may not be able to join:...

**Who might be able to join this trial:** - People who are 70 years of age or older, of any gender - People who are able to walk on their own, with or without a walking aid such as a cane or walker - People who have broken a bone after the age of 40, OR who have had two or more falls in the past 12 months, OR whose bon...

**Who might be able to join this trial:** - People aged 40 to 95 years old, of any gender - People who have been admitted to hospital with a spinal fracture (a collapsed vertebra) caused by either osteoporosis or an injury - People whose fracture is located in a specific section of the mid-to-lower spine (between the...

**Who might be able to join this trial:** - People aged 18 years or older - People who attend a Physical Medicine and Rehabilitation outpatient clinic - People who are already scheduled to have a routine bone density scan (called a DXA scan) as part of their normal clinical care - People who are physically able to perf...

**Who might be able to join this trial:** - People who are female - People aged 45 years or older - People who have gone through menopause - People who are already attending a Physical Medicine and Rehabilitation outpatient clinic - People who are already having a routine bone density scan (DEXA) and related blood test...