Brain Cancer Trial, Recruiting NCT05954858 Sponsor: Northwell Health Condition: Brain Cancer
Back to Brain Cancer

Brain Cancer Trial, Recruiting

NCT05954858
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 or older, of any gender
  • People who are scheduled to have surgery to remove a known or suspected brain tumour called glioblastoma (GBM)
  • People with a general health and functioning level of 70% or higher on a standard medical scale called the Karnofsky Performance Status (confirm with trial site)
  • People expected to live at least 6 months, in the opinion of the treating doctor
  • People whose neurosurgeon believes at least 80% of the tumour's active (enhancing) region can be removed during surgery
  • People who are able to have an MRI scan
  • People whose blood test results meet certain levels for immune cells, platelets, red blood cells, liver function, and kidney function (the trial site will check these)
  • Women who could become pregnant must have a negative blood pregnancy test and be willing to use an acceptable form of contraception
  • Men who could father a child must be willing to use an acceptable form of contraception with their partner
  • People who are able to understand and willing to sign a consent form (a legal representative may do this on someone's behalf)
  • People confirmed during surgery to have WHO Grade IV glioblastoma multiforme (GBM) based on tissue analysis
  • People for whom a specific type of tissue flap used in the procedure is technically possible during surgery (confirm with trial site)

Who may not be able to join:

  • Women who are pregnant or breastfeeding
  • People who have already started chemotherapy or radiation therapy for GBM
  • People who plan to take part in another clinical trial at the same time
  • People who plan to have a different treatment called Gliadel® wafer implanted during the same surgery
  • People who currently have an active infection that requires treatment
  • People whose scans show the tumour has spread to multiple areas of the brain or to the lining of the brain and spinal cord
  • People with a history of another cancer, unless they have been cancer-free for at least 5 years — though certain skin cancers (basal cell or squamous cell), and localised prostate or cervical cancer that has been successfully treated, may still be eligible (confirm with trial site)
  • People who have tested positive for HIV, or who have an active hepatitis B or hepatitis C infection
  • People with another significant medical condition that the trial team believes could put them at risk or affect how the study is carried out

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: John Boockvar, MD, Feinstein Institute for Medical Research/Lenox Hill Hospital

Phone: 212-434-3900

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Northwell Health
Registry
ClinicalTrials.gov
Start date
29 June 2023
Est. completion
30 June 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Progression Free Survival (PFS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov