Phase 2 PTSD Trial, Recruiting NCT05959434 Sponsor: Texas A&M University Condition: PTSD
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Phase 2 PTSD Trial, Recruiting

NCT05959434
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People of any gender identity, race, or ethnicity who are 18 years of age or older
  • People who are able to sign a written consent form agreeing to take part
  • People who are able to understand English
  • People who have been diagnosed with moderate to severe alcohol use disorder in the past month, based on standard diagnostic guidelines (meeting 4 or more criteria)
  • People who have had at least 3 to 4 heavy drinking days per week in the last 30 days, or who have drunk heavily for at least 2 weeks in the past month — with specific drink thresholds depending on gender (confirm with trial site for exact numbers)
  • People who have been diagnosed with PTSD in the past month, assessed using a specific structured clinical interview called the CAPS-5
  • People who also have a mood disorder (other than bipolar disorder) or an anxiety disorder, as these conditions commonly occur alongside alcohol use disorder and PTSD
  • People who also use other substances, as long as alcohol is their main substance of concern
  • People who are already taking psychiatric medications, provided the dose has been stable for at least 4 weeks before the study begins

Who may not be able to join:

  • People who have a current or past history of a psychotic disorder or bipolar disorder, or who are at immediate risk of harming themselves or others
  • People who have started a new psychiatric medication within the past 4 weeks
  • People currently experiencing acute alcohol withdrawal, indicated by a score above 8 on a standard withdrawal scale called the CIWA-Ar (these individuals may be re-evaluated after completing a medically supervised detox program)
  • Women who are pregnant or breastfeeding
  • People who are currently enrolled in a structured, evidence-based treatment program specifically for alcohol use disorder or PTSD (attendance at other activities such as Alcoholics Anonymous will be monitored throughout the study)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Anka A Vujanovic, Ph.D., Texas A&M University

Phone: 979-862-6538

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Texas A&M University
Registry
ClinicalTrials.gov
Start date
1 April 2024
Est. completion
30 June 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in Alcohol Use; Change in Posttraumatic Stress Disorder (PTSD) Symptoms

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov