Phase 2 Bipolar Disorder Trial, Recruiting NCT05977023 Sponsor: China Medical University Hospital Condition: Bipolar Disorder
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Phase 2 Bipolar Disorder Trial, Recruiting

NCT05977023
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are between 18 and 65 years old
  • People who have been diagnosed with Bipolar I Disorder (type 1) and are currently experiencing a depressive episode, according to standard psychiatric diagnostic guidelines
  • People who have been on a stable dose of certain mood-related medications — specifically quetiapine, lurasidone, or a mood stabilizer — for at least 4 weeks before joining
  • People whose depression symptoms score at a certain level of severity, and whose manic symptoms score at a low level, based on standard rating scales measured at the start of the trial
  • People who agree to take part and sign a consent form

Who may not be able to join:

  • People who currently misuse substances or have had a substance dependence problem in the past 6 months
  • People with a history of epilepsy, significant head injury, stroke, or other serious medical or neurological conditions that could interfere with the study
  • People who have been diagnosed with schizophrenia or another psychotic disorder
  • People assessed as having a moderate to severe risk of suicide
  • People with serious difficulties in thinking, memory, or cognitive functioning
  • People whose routine blood or laboratory test results show clinically significant abnormalities
  • People who are pregnant or breastfeeding
  • People who would be unable to follow the study procedures as required

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 14 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 886 4 22052121

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
China Medical University Hospital
Registry
ClinicalTrials.gov
Start date
4 October 2023
Est. completion
1 November 2027

Where this trial is recruiting

🇹🇼 Taiwan

Primary endpoints

Change in Visual Continuous Performance Test; Change in Wisconsin Card Sorting Test; Change in Logical Memory Test of the Wechsler Memory Scale; Digit Span; Spatial Span; Category Fluency; Trail Marking A; WAIS-III Digit Symbol-Coding; Mayer-Salovey-Caruso Emotional Intelligence Test (MSCEIT) V2.0; Change in Perceived Stress Scale in Perceived Stress Scale

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov