Brain Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Adults aged 18 or older, of any gender
- People who are scheduled to have surgery to remove a known or suspected brain tumour called glioblastoma (GBM)
- People whose general health and functioning is rated at 70% or above on a standard medical scoring scale (confirm with trial site)
- People whose treating doctor estimates they have a life expectancy of at least 6 months
- People whose neurosurgeon believes that at least 80% of the active tumour area can be removed during surgery
- People who are able to have an MRI scan
- People whose blood test results meet certain minimum levels for white blood cells, infection-fighting cells, platelets, haemoglobin, liver function, and kidney function (confirm with trial site for specific values)
- Women who could become pregnant must have a negative pregnancy blood test and be willing to use an accepted form of contraception
- People who are able to understand and willing to sign a consent form approved by an ethics review board
- People confirmed during surgery to have a recurrent Grade IV glioblastoma (GBM), based on tissue analysis
- People for whom a specific surgical technique involving tissue from the abdomen (called an omental graft) is found to be possible during the operation
Who may not be able to join:
- Women who are pregnant or breastfeeding
- People who plan to take part in another clinical trial at the same time
- People who plan to receive a treatment called Gliadel® wafers during this surgery
- People who currently have an active infection that requires treatment
- People whose scans show the tumour has spread to multiple areas of the brain or to the lining around the brain and spinal cord
- People with a history of another cancer, unless they have been free of that cancer for at least 5 years (certain skin cancers and some localised cancers that have been fully treated may be exceptions — confirm with trial site)
- People who have tested positive for HIV, or who have an active hepatitis B or hepatitis C infection
- People with another significant medical condition or history that the trial team believes could affect their safety or the results of the study
- People who have had previous abdominal surgery that a surgeon believes makes the omental graft procedure riskier or not feasible
- People with severe kidney problems that make a certain type of MRI scan (using a contrast dye called gadolinium) unsafe
- People who are unable to have an MRI scan for any reason
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: John Boockvar, MD, Northwell Health
Phone: 212-434-3900
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Safety parameter: proportion of patients experiencing rapidly progressive disease as indicated by MRI using RANO Criteria harvested omental graft for recurrent glioblastoma multiforme (rGBM).; Safety parameter: proportion of patients experiencing increase in seizures, stroke, and infection.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.