Obesity Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are able to give informed consent to participate
- People aged between 18 and 75 years old
- People with a BMI of 40 or above, or a BMI of 35 or above along with a health condition related to obesity
- People who are scheduled to have a primary weight-loss surgery — either a gastric bypass (Roux-en-Y) or a sleeve gastrectomy
- People whose weight has been stable for the 3 months before joining (meaning less than 10% change in body weight during that time)
For a smaller sub-group within the trial, additional criteria apply. People who may be eligible for this sub-group include:
- People who are able to give informed consent to participate
- People aged between 18 and 75 years old
- People with a BMI of 40 or above, or a BMI of 35 or above along with a health condition related to obesity
- People scheduled specifically for a gastric bypass (Roux-en-Y) surgery
- People whose body does not respond well to insulin, shown by higher-than-normal fasting blood sugar or insulin levels (confirm with trial site)
- Women who have been through menopause
Who may not be able to join:
- People who have any significant health condition other than obesity-related conditions, or thyroid problems that are well managed with treatment
- People who expect to become pregnant within the first two years after surgery
For the sub-group, additional exclusion criteria apply:
- People who have a blood clotting disorder or who take blood-thinning medications
- People who take any medications other than statins, certain blood pressure medications, or thyroid hormone medication (confirm with trial site for specific medication details)
- People who have been diagnosed with type 2 diabetes
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Mireille JM Serlie, Prof. Dr., Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Phone: +31703204703
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Predictors of improvement in metabolic health - insulin sensitivity; Predictors of improvement in metabolic health - level of glucose control; Predictors of improvement in metabolic health - glucose; Predictors of improvement in metabolic health - insulin; Predictors of improvement in metabolic health - lipid profile; Predictors of improvement in metabolic health - biomarker inflammation; Predictors of improvement in metabolic health; Predictors of weight loss
Can't join this trial?
Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.