Phase 1 Interstitial Lung Disease Trial, Recruiting NCT05988463 Sponsor: Joseph C. Wu Condition: Interstitial Lung Disease
Back to Interstitial Lung Disease

Phase 1 Interstitial Lung Disease Trial, Recruiting

NCT05988463
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 40 years or older.
  • People who have been diagnosed with IPF (idiopathic pulmonary fibrosis) according to specific international guidelines from 2018.
  • People whose lungs are still able to hold and move at least 40% of the expected amount of air for someone their age and size (based on a breathing test called FVC, taken within the last 3 months).
  • People whose lungs are still able to transfer at least 30% of the expected amount of oxygen into the blood (based on a test called DLco, taken within the last 3 months).
  • People who are currently taking nintedanib or pirfenidone for IPF, as long as the dose has been stable for at least 6 weeks before the screening visit.
  • People who are able to use highly reliable birth control (99% or more effective) throughout the study and for 60 days after the last dose of the study drug — this applies to women who could become pregnant and to men whose partners could become pregnant.
  • People who agree not to donate eggs or sperm during the study and for 60 days after the last dose of the study drug.
  • People who are able to read and sign a consent form agreeing to take part.

Who may not be able to join:

  • People who are currently taking an unapproved treatment for IPF-related scarring, or who are already participating in another clinical trial.
  • People who have signs of an active infection (such as bronchitis, pneumonia, or a sinus infection) that could affect breathing test results during screening.
  • People who have had a sudden worsening of their IPF in the 3 months before screening, or where the trial doctor suspects this may have occurred.
  • People whose lung scans show that the extent of air sac damage (emphysema) is greater than the extent of scarring (fibrosis), as assessed by the trial doctor.
  • People who have a significant medical condition — such as heart, liver, or kidney disease, or a recent cancer — that the trial doctor considers would make participation unsuitable.
  • People whose liver function blood test results are above certain limits set by the trial (confirm with trial site for exact values).
  • People whose haemoglobin (a measure of red blood cells) is below 10.0 g/dL.
  • People who are pregnant or breastfeeding.
  • People who are expected to receive a lung transplant during the study period (being on a transplant waiting list is acceptable).
  • People who are currently taking, and expected to continue taking, any of the following medications during the study: amodiaquine, efavirenz, nevirapine, or ritonavir.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Joshua Mooney, MD, Stanford University

Phone: (650) 736-2246

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Joseph C. Wu
Registry
ClinicalTrials.gov
Start date
1 January 2027
Est. completion
1 November 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Number of participants who experience treatment-related adverse events

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov