OCD Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You have been diagnosed with obsessive-compulsive disorder (OCD) by three separate psychiatrists who are not your regular treatment team.
- Your OCD has been rated as severe using a specific OCD scoring tool called the Yale-Brown scale, with a score above 25.
- Your OCD symptoms have been severe and significantly affecting your life for more than 5 years, even after receiving treatment.
- You have tried at least two different medications that affect serotonin in the brain, plus one additional medication to boost their effect, for a long enough period, without enough improvement.
- You have tried an appropriate course of talking therapy (psychotherapy) without enough improvement.
- You meet the medical requirements to have a deep brain stimulation (DBS) device surgically implanted (confirm with trial site).
- You are between 18 and 75 years old.
- You are able to understand and sign a written consent form agreeing to take part.
Who may not be able to join:
- You have severe depression that also includes psychotic features (such as hallucinations or delusions).
- You are considered to have a significant risk of suicide, based on a specific rating scale score (confirm with trial site).
- You have also been diagnosed with a primary psychotic disorder, bipolar disorder, PTSD, an eating disorder, or autism spectrum disorder.
- You have had a problem with alcohol or drug misuse or dependence in the past 12 months.
- You have significant memory or thinking difficulties, identified through specific cognitive tests (confirm with trial site).
- You have another significant neurological condition or illness affecting how your brain works, other than a tic disorder.
- A brain scan (MRI) taken before any surgery shows a significant abnormality.
- You have any medical reason that would make deep brain stimulation surgery unsafe, such as a serious infection, blood clotting problems, or significant heart problems.
- You are currently pregnant.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Idit Idit, Rabin Medical Center
Phone: +972 3 9376406
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Assessment of the efficacy of amSTN/MFB stimulation on OCD symptoms - YBOCS score (0-40); Assessment of the efficacy of amSTN/MFB stimulation on OCD symptoms - YBOCS score (0-40); Assessment of the efficacy of amSTN/MFB stimulation on OCD symptoms - YBOCS score (0-40); Assessment of the efficacy of amSTN/MFB stimulation on OCD symptoms - YBOCS score (0-40); Assessment of the association between amSTN electrophysiological discharge and cognitive/ emotional measures; Assessment of the association between amSTN electrophysiological discharge and cognitive/ emotional measures; Assessment of the as...
Can't join this trial?
Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.