Chronic Kidney Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are 18 years of age or older
• People who have been referred to have a new arteriovenous fistula (AVF) — a surgically created connection between an artery and vein, often used for dialysis access — created for the first time
• People who are willing and able to follow the study requirements, stay in contact with the study team, and attend check-up visits over 36 months

Who may not be able to join:

• People whose planned surgery is to fix or update an existing fistula, rather than create a new one
• People whose target artery measures less than 2.0 mm across on the inside, as measured by ultrasound during the procedure preparation
• People whose target vein measures less than 2.0 mm across on the inside, as measured by ultrasound during the procedure preparation
• People who have a significant narrowing (50% or more) in the target vein on the side where surgery is planned, as found by ultrasound before the operation
• People with a known significant narrowing (50% or more) in the large veins near the centre of the chest, on the side of the planned surgery
• People who have a mesh tube (stent) or covered mesh tube already placed within the area where the fistula would be created
• People with a known or suspected blood clotting disorder that the study doctor believes would make fistula surgery too risky
• People with a known or suspected active infection at the time of surgery
• People with severe heart failure classified at the highest level of severity (confirm with trial site)
• People who have previously experienced a condition where the fistula caused reduced blood flow to the hand or arm on the same side as the planned surgery
• People currently enrolled in another clinical study involving an experimental drug, device, or biological treatment, or who were previously enrolled in this same study
• People with a life expectancy of less than 12 months
• People expected to have a kidney transplant within 6 months of joining the study
• People expected to do dialysis at home
• Women who could become pregnant (i.e., who have not gone through menopause and have not had sterilisation surgery) without a documented negative pregnancy test at the screening stage
• People with another health condition that the study doctor believes would make it difficult to collect reliable and safe study data
• People who are unwilling or unable to give consent or follow the study visit schedule
• People with any health condition that, in the study doctor's opinion, could affect their safety or their ability to take part in the study

Important: Always verify eligibility with the trial site directly before applying.