PTSD Trial, Recruiting NCT06002633 Sponsor: University of Texas at Austin Condition: PTSD
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PTSD Trial, Recruiting

NCT06002633
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are between 21 and 60 years old
  • In the past year, you have had at least 4 drinks (if male) or at least 3 drinks (if female) on at least two separate occasions
  • If joining as a PTSD participant: you have been diagnosed with PTSD, confirmed through a structured interview

Who may not be able to join:

  • You have a history of a serious medical illness, especially one that may have affected brain tissue
  • You have a neurological condition, or have had a significant head injury that caused you to lose consciousness for 5 minutes or more
  • Your IQ score is below 85 (confirm with trial site)
  • You have any reason you cannot have an MRI scan (for example, a metal implant)
  • You have a positive pregnancy test
  • You have a severe alcohol use disorder
  • You currently have a severe cannabis use disorder
  • You currently have a substance use disorder involving any substance other than alcohol, cannabis, or nicotine
  • You scored above 15 on a standard alcohol use screening questionnaire called the AUDIT
  • You have ever been in a treatment program focused on stopping alcohol use completely
  • You have said you want to quit drinking but feel unable to
  • You have a medical, religious, or personal reason that prevents you from drinking alcohol
  • You have a history of heart attack, heart problems, high blood pressure, diabetes, or liver disease
  • You have had a bad reaction to alcoholic drinks in the past
  • You have not had 4 drinks or more (men) or 3 drinks or more (women) on at least two occasions in the past year
  • You are unwilling to have a friend or family member drive you home after sessions where alcohol is given
  • If joining as a PTSD or intimate partner violence (IPV)-exposed participant: you have been on a medication for less than 4 weeks (meaning you need to be on a stable medication routine)
  • If joining as a PTSD or IPV-exposed participant: you are currently having thoughts of suicide with intent to act
  • If joining as an IPV-exposed but no PTSD participant: you have a history of PTSD
  • If joining as a healthy comparison participant: you have ever been hospitalised for a psychiatric reason
  • If joining as a healthy comparison participant: you have a lifetime history of a neurodevelopmental disorder, mood disorder, psychotic disorder, eating disorder, or a history of a suicide attempt
  • If joining as a healthy comparison participant: you have taken psychiatric medication for more than one month total in your lifetime

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Elizabeth Lippard, PhD, University of Texas at Austin

Phone: 5124955198

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
University of Texas at Austin
Registry
ClinicalTrials.gov
Start date
23 October 2023
Est. completion
31 May 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

ratio of approach to avoidance choices; changes in dorsal anterior cingulate cortex activation; Relations between ratio of approach to avoidance choices with alcohol use over a one-year follow-up; Relations between changes in dorsal anterior cingulate cortex activation with alcohol use over a one-year follow-up

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov