Lung Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with non-small cell lung cancer, confirmed by a tissue or cell sample test.
• People whose cancer is classified as stage IIIA, IIIB, or IIIC using the standard international cancer staging system (8th edition).
• People whose cancer cannot be removed by surgery, or who have declined surgery, after receiving initial treatment with immunotherapy and chemotherapy combined with radiation.
• People who received at least 2 cycles of initial chemotherapy combined with immunotherapy, and whose cancer responded by shrinking, disappearing, or at least showing a decreasing trend (not growing).
• People with a performance status score of 0 or 1, meaning they are fully active or have only minor limitations in daily activity (confirm with trial site).
• People who have at least one tumour that can be measured or assessed on scans.
• People whose life expectancy is at least 6 months.
• People with adequate heart, lung, kidney, liver, and bone marrow function.

Who may not be able to join:

• People whose cancer continued to grow during the initial immunotherapy and chemotherapy treatment.
• People whose cancer has certain genetic mutations — specifically EGFR, ALK, or ROS1 mutations.
• People who have previously had radiation treatment to the chest area.
• People who experienced moderate or severe immune-related side effects (grade 2 or higher) during their initial immunotherapy.
• People with a history of another cancer, except for early-stage non-melanoma skin cancer or cervical carcinoma in situ.
• People who are pregnant or breastfeeding.
• People who are currently participating in another clinical trial.
• People with serious other health conditions, including heart attack, severe irregular heartbeat, severe stroke-related disease, ulcer disease, serious mental illness, or uncontrolled diabetes.
• People who are HIV-positive and currently receiving antiviral treatment for HIV.
• People with active tuberculosis.

Important: Always verify eligibility with the trial site directly before applying.