Phase 1 Leukaemia Trial, Recruiting NCT06034275 Sponsor: Vincerx Pharma, Inc. Condition: Leukaemia
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Phase 1 Leukaemia Trial, Recruiting

NCT06034275
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with AML (a type of blood cancer), B-ALL (another type of blood cancer), or MDS (a bone marrow disorder), confirmed through laboratory testing of tissue samples.
  • People whose condition has not responded to all available standard treatments, or where standard treatments have been determined to not be suitable for them.
  • People whose bone marrow or blood tests show at least 5% abnormal cells (blasts), which allows the trial team to measure whether the treatment is working.
  • People whose cancer cells have tested positive for a specific protein called CD123, confirmed through local laboratory testing.
  • People whose general physical health and ability to carry out daily activities falls within a certain range on a standard medical scale (scored 0 to 2 out of 5, where 0 means fully active and 2 means up and about more than half of waking hours) (confirm with trial site).

Who may not be able to join:

  • People whose cancer has spread to the brain or the lining around the brain and spinal cord.
  • People with significant heart conditions, including heart failure above a certain level of severity, unstable chest pain (including chest pain that occurs at rest), newly diagnosed chest pain within the last 6 months, or a heart attack within the 6 months before starting the trial.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 12 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Vincerx Study Director, Vincerx Pharma, Inc.

Phone: 16508006676

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Vincerx Pharma, Inc.
Registry
ClinicalTrials.gov
Start date
13 September 2023
Est. completion
30 May 2025

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Incidence of DLT (Dose limit toxicity) of VIP943

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov