Endometrial Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are 18 years old or older
• People who have been diagnosed with a specific type of uterine cancer called low-grade endometrioid adenocarcinoma, at stages I to III (using FIGO 2009 staging)
• People who finished surgery and any follow-up cancer treatment between 1 month and 10 years ago
• People with a Body Mass Index (BMI) between 25 and 45 kg/m²
• People who are willing and able to follow the study's activities and check-ins throughout the trial
• People who show a readiness to work toward a healthier weight, as measured by a questionnaire
• People who have a smartphone that works with the Fitbit app, with internet access and Bluetooth
• People who can speak, read, and understand English

Who may not be able to join:

• People whose uterine cancer has come back (in the same area or spread elsewhere) or has spread to other parts of the body
• People who have an abnormal p53 gene result combined with a stage III or IV cancer diagnosis (confirm with trial site)
• People whose weight has gone up or down by more than 5 kg in the past 3 months
• People who have surgery planned within the next 6 months
• People who have previously had weight-loss (bariatric) surgery
• People with a thyroid condition that is not well controlled
• People with Type 1 diabetes
• People with Type 2 diabetes whose blood sugar levels are poorly controlled (HbA1c above 10%), or who are currently taking insulin, sulfonylureas, or GLP-1 medications for diabetes
• People currently taking corticosteroid medications (a type of steroid)
• People currently taking prescription weight-loss medications
• People who currently smoke in any form, including cigarettes, e-cigarettes, vaping, or marijuana
• People who are already doing more than 90 minutes per week of moderate-intensity aerobic exercise on average over the past 3 months
• People for whom exercise or exercise testing may pose a safety risk, based on a health screening questionnaire and heart health assessment (confirm with trial site)
• People with physical or mobility limitations that would prevent them from doing physical activity
• People who have been following a structured low-calorie diet, a meal replacement program, a weight-loss meal plan, intermittent fasting, or a high-fat diet in the past 3 months — or people who have been following a vegan diet for less than two years
• People with a history of an eating disorder that was diagnosed by a doctor
• People who plan to be away for more than 2 weeks in a row during the study and would not be able to follow the study requirements during that time
• People with active problems related to substance use, including alcohol, cannabis, or other drugs
• People for whom a DXA scan or MRI scan is not safe (for example, those with a pacemaker or who are pregnant)
• People who are unable to take part in phone or video sessions due to significant hearing or vision difficulties
• People who are unable to follow the study requirements — for example, those who cannot commit to scheduled group video sessions, have very limited internet access, are not willing to use the study's online platform, have been advised by a health professional not to lose weight or reduce food intake, or who have cognitive impairment or dementia
• People who are unable to travel to the study location
• People who are unable to provide written consent to participate

Important: Always verify eligibility with the trial site directly before applying.