Phase 2 Brain Cancer Trial, Recruiting NCT06055790 Sponsor: University of Arizona Condition: Brain Cancer
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Phase 2 Brain Cancer Trial, Recruiting

NCT06055790
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been clinically suspected of having, or diagnosed with, one or more tumours that have spread to the brain (brain metastases)
  • People aged 18 years or older
  • People with a known history of cancer
  • People who have had a brain MRI scan within the past 2 months that showed signs of cancer spread to the brain
  • People who are already scheduled to receive one of the following treatments: surgical removal of the brain lesion(s), a targeted type of radiation called stereotactic radiosurgery, or whole-brain radiation therapy
  • People who are physically able to lie still on their back for the full duration of a PET/CT scan
  • People who are willing and able to read and sign a written consent form agreeing to take part

Who may not be able to join:

  • People who have had a brain biopsy of the lesion(s) being studied less than 4 weeks before the PET/CT scan (this waiting period helps avoid misleading scan results caused by inflammation)
  • People who have already had surgery or radiation treatment on the specific brain lesion(s) being studied in this trial
  • People who have received any treatment for the brain lesion(s) being studied, or started a new whole-body (systemic) cancer treatment, after their most recent MRI and before the PET/CT scan
  • People whose only brain lesion(s) being studied are located within the treated area of a previous brain radiation treatment — however, if at least one lesion falls outside that previously treated area, participation may still be possible (confirm with trial site)
  • People who are unable to lie still for the PET/CT scan
  • People whose participation in the trial would cause a delay to their standard medical care

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Bital Savir-Baruch, MD, University of Arizona

Phone: 520-626-0375

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
University of Arizona
Registry
ClinicalTrials.gov
Start date
10 September 2024
Est. completion
31 October 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Characterization of the dynamics of 18F-fluciclovine uptake within a metastatic brain lesion over 60 mins.; Assessment of the dynamics of 18F-fluciclovine uptake within recently treated metastatic brain lesions.; Evaluate the potential use of 18F-fluciclovine in delineating true local progression from radionecrosis in patients with clinical uncertainty of indeterminate MRI.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov