Phase 3 Myasthenia Gravis Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• In the USA: you must be between 12 and 17 years old when you sign the consent form; in most other countries, children aged 2 to 17 years old may be eligible
• You have been diagnosed with generalized myasthenia gravis (a muscle weakness condition), confirmed by a blood test showing a specific antibody (called AChR) before the study screening
• Your myasthenia gravis falls into a moderate-to-severe category based on a standard medical rating scale (MGFA Classification II to IV) at the time of screening
• If you are aged 12 to 17: your myasthenia gravis symptoms score 6 or higher on a daily activities assessment called the MG-ADL scale at screening
• If you are aged 2 to 11 (outside the USA only): your doctor has recorded weakness in at least one limb, your neck, or muscles used for swallowing or speaking
• You have been vaccinated against meningococcal infection within the past 3 years, or you are able to receive this vaccination and take antibiotics until at least 2 weeks after the vaccine

Who may not be able to join:

• You have tested positive for a different antibody called muscle-specific kinase (MuSK)
• You have a medical or mental health condition that the study doctor believes could affect your ability to safely take part in the trial
• You have had surgery to remove your thymus gland within the past 6 months
• Your myasthenia gravis symptoms are considered minimal or nearly gone, based on your doctor's assessment
• You have had a general infection in the past 2 weeks, or an infection requiring IV (drip) antibiotics in the past 4 weeks before starting the study

Important: Always verify eligibility with the trial site directly before applying.